Barford, D., Keller, J. C. (January 1994) Co-crystallization of the catalytic subunit of the serine/threonine specific protein phosphatase 1 from human in complex with microcystin LR. J Mol Biol, 235 (2). pp. 763-6. ISSN 0022-2836 (Print)
Abstract
The catalytic subunit of the serine/threonine specific protein phosphatase 1 from human (molecular mass 37 KDa) has been co-crystallized in complex with the cyanobacterial toxin microcystin LR (molecular mass 1 kDa). The crystals diffract to a resolution of 2.8 A when exposed to synchrotron radiation and belong to space group P2(1)2(1)2 with a = 109.5 A, b = 90.6 A, c = 38.7 A. There is one molecule of protein phosphatase 1 per asymmetric unit. The crystal form is suitable for the determination of the atomic structure of protein phosphatase 1.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Crystallization Crystallography, X-Ray Humans Peptides, Cyclic/ chemistry Phosphoprotein Phosphatase/ chemistry Research Support, Non-U.S. Gov't Serine Threonine |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > protein phosphatase Investigative techniques and equipment > x ray crystallography |
| CSHL Authors: | |
| Communities: | CSHL labs > Hengartner lab CSHL labs > Stillman lab |
| Depositing User: | Matt Covey |
| Date: | 14 January 1994 |
| Date Deposited: | 04 May 2015 14:50 |
| Last Modified: | 04 May 2015 14:50 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/31477 |
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