Functional properties of non-muscle tropomyosin isoforms

Pittenger, M. F., Kazzaz, J. A., Helfman, D. M. (February 1994) Functional properties of non-muscle tropomyosin isoforms. Curr Opin Cell Biol, 6 (1). pp. 96-104. ISSN 0955-0674 (Print)

DOI: 10.1016/0955-0674(94)90122-8


Tropomyosins are a family of actin filament binding proteins. They have been identified in many organisms, including yeast, nematodes, Drosophila, birds and mammals. In metazoans, different forms of tropomyosin are characteristic of specific cell types. Most non-muscle cells, such as fibroblasts, express five to eight isoforms of tropomyosins. The various isoforms exhibit distinct biochemical properties that appear to be required for specific cellular functions.

Item Type: Paper
Uncontrolled Keywords: Actins/metabolism Animals Cell Movement/ physiology Comparative Study Genes Humans Muscles/physiology Organ Specificity Protein Binding Rats Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Tropomyosin/chemistry/genetics/ metabolism
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > myosin
CSHL Authors:
Communities: CSHL labs > Helfman lab
Depositing User: Matt Covey
Date: February 1994
Date Deposited: 24 Jun 2015 19:40
Last Modified: 24 Jun 2015 19:40
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