Plastic genes are in!

Silva, A. J., Giese, K. P. (June 1994) Plastic genes are in! Curr Opin Neurobiol, 4 (3). pp. 413-20. ISSN 0959-4388 (Print)

DOI: 10.1016/0959-4388(94)90104-X


Even though the synthesis of new proteins is thought to be essential for long-term changes in synaptic plasticity, as well as for long-term memory, little is known about the identity of the required proteins. The hunt for these molecules is under way, however, and in the past year several groups of researchers have entered this fascinating search by introducing new approaches that have lead to the identification of several potential candidates, amongst which are trophic factors, kinases, ion channels, and proteases. The results will have much to say not only about the nature of memory, but also about the mechanisms of learning.

Item Type: Paper
Uncontrolled Keywords: Animals Aplysia/physiology Cyclic AMP Response Element-Binding Protein/physiology DNA-Binding Proteins/physiology Early Growth Response Protein 1 Genes Gills/physiology Humans Immediate-Early Proteins Long-Term Potentiation Memory/physiology Models, Neurological Neuronal Plasticity/ physiology Synapses/physiology Transcription Factors/physiology
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: June 1994
Date Deposited: 26 Aug 2015 21:10
Last Modified: 26 Aug 2015 21:10
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