[The German Study on the Epidemiology of Parkinson's Disease with Dementia (GEPAD): more than Parkinson]

Von Reichmann, H., Deuschl, G., Riedel, O., Spottke, A., Forstl, H., Henn, F., Heuser, I., Oertel, W., Riederer, P., Trenkwalder, C., Dodel, R., Wittchen, H. U. (April 2010) [The German Study on the Epidemiology of Parkinson's Disease with Dementia (GEPAD): more than Parkinson]. MMW Fortschr Med, 152 Su. pp. 1-6. ISSN 1438-3276 (Print)1438-3276

URL: http://www.ncbi.nlm.nih.gov/pubmed/20942300


It is unknown, how frequently Parkinson's disease (PD) is complicated by dementia, depression and other neuropsychiatric conditions. An epidemiologic characterisation of the situation in specialised neurologic settings is lacking. The Geman Study on the Epidemiology of Parkinson's Disease with Dementia (GEPAD) isa national representative epidemiological study of n=1449 PD patients in n=315 office-based neurological settings, designed to estimate the prevalence of dementia, depression and other neuropsychiatric conditions in patients with PD of all stages by using standardized clinical assessments. RESULTS: 28.6% met DSM-IV criteria for dementia. 33.6% met criteria for depression and 61% additionally had other clinically significant psychopathological syndromes. Only 29.4% had no neuropsychiatric conditions. GEPAD reveals for the first time comprehensively that the neuropsychiatric burden of PD patients in all stages and even early stages is considerable, posing challenging questions for research and clinical management.

Item Type: Paper
Uncontrolled Keywords: Aged Cognition Disorders/classification/diagnosis/*epidemiology Comorbidity Cross-Sectional Studies Depressive Disorder/classification/diagnosis/epidemiology Female Germany Humans Lewy Body Disease/classification/diagnosis/*epidemiology Male Mass Screening Mental Status Schedule Middle Aged Neurologic Examination Neuropsychological Tests Parkinson Disease/classification/diagnosis/*epidemiology
Subjects: diseases & disorders > mental disorders > delirium dementia cognitive disorders
diseases & disorders > nervous system diseases and disorders > Parkinson's disease
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date: 8 April 2010
Date Deposited: 06 Jun 2014 16:25
Last Modified: 06 Jun 2014 16:25
URI: https://repository.cshl.edu/id/eprint/30275

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