Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., Hermjakob, H., Stein, L., D'Eustachio, P. (January 2014) The Reactome pathway knowledgebase. Nucleic Acids Research, 42 (Databa). D472-7. ISSN 0305-1048
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Abstract
Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | *Databases, Protein Disease Humans Internet Knowledge Bases Metabolic Networks and Pathways Proteins/*metabolism |
| Subjects: | bioinformatics bioinformatics > genomics and proteomics bioinformatics > genomics and proteomics > databases > databases bioinformatics > genomics and proteomics > datasets |
| CSHL Authors: | |
| Communities: | CSHL labs > Stein lab |
| Depositing User: | Matt Covey |
| Date: | January 2014 |
| Date Deposited: | 11 Apr 2014 18:38 |
| Last Modified: | 11 Apr 2014 18:38 |
| PMCID: | PMC3965010 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/29749 |
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