Powers, S. (August 1992) Genetic analysis of ras homologs in yeasts. Semin Cancer Biol, 3 (4). pp. 209-18. ISSN 1044-579X (Print)1044-579x
Abstract
Ras proteins with extensive structural homology to mammalian p21ras have been studied in the two yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Comparative analysis of these two yeasts has revealed significant differences in the biochemical and physiological functions that are controlled by this subgroup of eukaryotic GTP-binding regulatory proteins. Despite such divergence of cellular functions, proteins and mechanisms involved in the regulation and modification of Ras proteins are highly conserved in yeasts and other eukaryotes. Genetic analysis of the function of yeast proteins that regulate or modify Ras proteins has provided important information about Ras proteins in general.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Adenylate Cyclase/metabolism GTPase-Activating Proteins Gene Expression Regulation Genes, ras/*physiology Protein Processing, Post-Translational/physiology Proteins/physiology Saccharomyces cerevisiae/*genetics Schizosaccharomyces/*genetics ras GTPase-Activating Proteins |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein > Ras organism description > yeast |
| CSHL Authors: | |
| Communities: | CSHL labs > Powers lab |
| Depositing User: | Matt Covey |
| Date: | August 1992 |
| Date Deposited: | 25 Feb 2014 21:44 |
| Last Modified: | 25 Feb 2014 21:44 |
| URI: | https://repository.cshl.edu/id/eprint/29513 |
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