Interneuron cell types are fit to function

Kepecs, A., Fishell, G. (January 2014) Interneuron cell types are fit to function. Nature, 505 (7483). pp. 318-326. ISSN 0028-0836

URL: http://www.ncbi.nlm.nih.gov/pubmed/24429630

DOI: 10.1038/nature12983

Abstract

Understanding brain circuits begins with an appreciation of their component parts - the cells. Although GABAergic interneurons are a minority population within the brain, they are crucial for the control of inhibition. Determining the diversity of these interneurons has been a central goal of neurobiologists, but this amazing cell type has so far defied a generalized classification system. Interneuron complexity within the telencephalon could be simplified by viewing them as elaborations of a much more finite group of developmentally specified cardinal classes that become further specialized as they mature. Our perspective emphasizes that the ultimate goal is to dispense with classification criteria and directly define interneuron types by function.

Item Type:	Paper
Uncontrolled Keywords:	HIPPOCAMPAL NETWORK OSCILLATIONS CORTICAL GABAERGIC INTERNEURONS MEDIAL GANGLIONIC EMINENCE FATE MAPPING REVEALS FAST-SPIKING CELLS IN-VIVO CEREBRAL-CORTEX IMMUNOREACTIVE INTERNEURONS INHIBITORY INTERNEURONS STRIATAL INTERNEURONS
Subjects:	organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions > cell types organs, tissues, organelles, cell types and functions > cell types and functions > cell types > interneurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > interneurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > interneurons organs, tissues, organelles, cell types and functions > tissues types and functions > neural networks organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits
CSHL Authors:	Kepecs, Adam
Communities:	CSHL labs > Kepecs lab
Depositing User:	Matt Covey
Date:	January 2014
Date Deposited:	07 Feb 2014 21:53
Last Modified:	18 Jan 2017 15:46
PMCID:	PMC4349583
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/29489

Actions (login required)

Administrator's edit/view item