Transcriptional regulation: RUPture in the ER

Tansey, W. P. (October 2000) Transcriptional regulation: RUPture in the ER. Nature Cell Biology, 2 (10). E175-E177. ISSN 1465-7392

Abstract

Regulated ubiquitin/proteasome-dependent processing controls transcription by triggering the release of dormant transcriptional activators from the endoplasmic reticulum. This intersection of transcription and proteolysis has important implications for gene control, proteasome-substrate interactions and signal integration.

Item Type:	Paper
Uncontrolled Keywords:	UBIQUITIN-PROTEASOME PATHWAY NF-KAPPA-B PROTEIN ACTIVATION RSP5
Subjects:	bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription organs, tissues, organelles, cell types and functions > organelles, types and functions > endoplasmic reticulum bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein ubiquitination
CSHL Authors:	Tansey, William P.
Communities:	CSHL labs > Tansey lab
Depositing User:	Matt Covey
Date:	October 2000
Date Deposited:	28 Jan 2014 21:48
Last Modified:	28 Jan 2014 21:48
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/29452

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