Grewal, S. I. S., Elgin, S. C. (April 2002) Heterochromatin: new possibilities for the inheritance of structure. Current Opinion in Genetics & Development, 12 (2). pp. 178-187. ISSN 0959-437X
Abstract
Significant portions of the eukaryotic genome are heterochromatic, made up largely of repetitious sequences and possessing a distinctive chromatin structure associated with gene silencing. New insights into the form of packaging, the associated histone modifications, and the associated nonhistone chromosomal proteins of heterochromatin have suggested a mechanism for providing an epigenetic mark that allows this distinctive chromatin structure to be maintained following replication and to spread within a given domain.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics > heterochromatin |
| CSHL Authors: | |
| Communities: | CSHL labs > Grewal lab |
| Depositing User: | Matt Covey |
| Date: | April 2002 |
| Date Deposited: | 08 Jan 2014 21:30 |
| Last Modified: | 08 Jan 2014 21:30 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/28708 |
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