Onai, T., FitzGerald, M. G., Arakawa, S., Gocayne, J. D., Urquhart, D. A., Hall, L. M., Fraser, C. M., McCombie, W. R., Venter, J. C.
(1989)
Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor.
FEBS Letters, 255 (2).
pp. 219-225.
ISSN 00145793 (ISSN)
Abstract
Two cDNA clones (3.7 kb and 4.8 kb) encoding a Drosophila muscarinic acetylcholine receptor were isolated from a Drosophila head cDNA library and characterized by automated DNA sequence analysis. The Drosophila muscarinic receptor contains 788 amino acids with a calculated Mr of 84 807 and displays greater than 60% homology with mammalian muscarinic receptors. The muscarinic receptor maps to the tip of the right arm of the second chromosome of the Drosophila genome. © 1989.
| Item Type: |
Paper
|
| Uncontrolled Keywords: |
cDNA
DNA sequence analysis, automated
Receptor evolution
Receptor supergene family
Sequence homology
Signal sequence
DNA
muscarinic receptor
amino acid sequence
animal
article
chromosome map
comparative study
computer program
Drosophila melanogaster
genetics
molecular cloning
molecular genetics
nucleotide sequence
protein conformation
restriction mapping
structural gene
Base Sequence
Chromosome Mapping
Cloning, Molecular
Genes, Structural
Molecular Sequence Data
Receptors, Muscarinic
Sequence Homology, Nucleic Acid
Software
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S. |
| Subjects: |
bioinformatics > genomics and proteomics > analysis and processing
bioinformatics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
organism description > animal > insect > Drosophila
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics
Investigative techniques and equipment
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification
Investigative techniques and equipment > assays
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function
Investigative techniques and equipment > cloning
Investigative techniques and equipment > assays > cloning
organism description > animal > insect
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein receptor |
| CSHL Authors: |
|
| Communities: |
CSHL labs > McCombie lab |
| Depositing User: |
Matt Covey
|
| Date: |
1989 |
| Date Deposited: |
25 Apr 2013 17:56 |
| Last Modified: |
25 Apr 2013 17:56 |
| Related URLs: |
|
| URI: |
https://repository.cshl.edu/id/eprint/28200 |
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