Paddison, P. J. (2008) RNA interference in mammalian cell systems. In: RNA Interference. Curr Top Microbiol Immunol, 320 . Springer Verlag, Berlin; New York, pp. 1-19. ISBN 978-3-540-75156-4
Abstract
The use of RNA interference (RNAi) to evoke gene silencing in mammalian cells has almost become routine laboratory practice. Through refinement of double-stranded RNA (dsRNA) triggers of RNAi and creation of genome-scale libraries, the first genome-wide loss of function screens have been carried out in mammals. This review discusses some of the key features of RNAi in mammalian systems.
| Item Type: | Book Section |
|---|---|
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > design bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics Investigative techniques and equipment bioinformatics > genomics and proteomics > design > nucleic acid design Investigative techniques and equipment > RNAI bioinformatics > genomics and proteomics > design > nucleic acid design > RNAI Design bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi |
| CSHL Authors: | |
| Communities: | CSHL labs > Paddison lab |
| Depositing User: | Matt Covey |
| Date: | 2008 |
| Date Deposited: | 25 Feb 2013 17:18 |
| Last Modified: | 25 Feb 2013 17:18 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/27615 |
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