Muthuswamy, S. K. (October 2012) Autocrine prolactin: an emerging market for homegrown (prolactin) despite the imports. Genes Dev, 26 (20). pp. 2253-8. ISSN 1549-5477 (Electronic)0890-9369 (Linking)
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Abstract
Prolactin (PRL) is a peptide hormone that is produced by the pituitary gland and is known to regulate lactogenic differentiation. There is a significant body of evidence that points to autocrine production of prolactin and activation of an autocrine/paracrine signaling pathway to regulate cell proliferation and migration and inhibition of cell death. This perspective highlights the recent study in the October 1, 2012, issue of Genes & Development by Chen and colleagues (pp. 2154-2168) that describes a mechanism for autocrine prolactin production and places the finding in the context of a role for prolactin in breast development and cancer.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > cancer diseases & disorders organs, tissues, organelles, cell types and functions > organs types and functions > breast diseases & disorders > cancer > cancer types > breast cancer organs, tissues, organelles, cell types and functions > organs types and functions diseases & disorders > cancer > cancer types |
| CSHL Authors: | |
| Communities: | CSHL labs > Muthuswamy lab |
| Depositing User: | Matt Covey |
| Date: | 15 October 2012 |
| Date Deposited: | 30 Jan 2013 16:32 |
| Last Modified: | 03 Nov 2017 20:01 |
| PMCID: | PMC3475797 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/27008 |
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