Inhibition by α-amanitin of simian virus 40-specific ribonucleic acid synthesis in nuclei of infected monkey cells

Jackson, A. H., Sugden, B. (November 1972) Inhibition by α-amanitin of simian virus 40-specific ribonucleic acid synthesis in nuclei of infected monkey cells. J Virol, 10 (5). pp. 1086-9. ISSN 0022-538x

Abstract

Conditions affecting the synthesis of simian virus 40-specific ribonucleic acid (RNA) in nuclei isolated from lytically infected cells were investigated. Deoxyribonucleic acid-RNA hybridization results show that an -amanitin-sensitive RNA polymerase activity is responsible for transcription of simian virus 40 deoxyribonucleic acid.

Item Type: Paper
Uncontrolled Keywords: Animals Cell Line Cell Nucleus metabolism Cells, Cultured DNA Replication DNA, Viral biosynthesis DNA-Directed RNA Polymerases metabolism Haplorhini Kidney Mycotoxins pharmacology Nucleic Acid Hybridization Peptides pharmacology RNA biosynthesis RNA Viral antagonists & inhibitors/biosynthesis Simian virus 40 metabolism Transcription Genetic Tritium Uracil Nucleotides metabolism
Subjects: organism description > virus
CSHL Authors:
Communities: CSHL labs
Depositing User: CSHL Librarian
Date: November 1972
Date Deposited: 03 Apr 2012 19:34
Last Modified: 02 May 2016 20:35
Related URLs:
URI: https://repository.cshl.edu/id/eprint/25911

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