Albeanu, D. F., Soucy, E., Sato, T. F., Meister, M., Murthy, V. N. (2008) LED arrays as cost effective and efficient light sources for widefield microscopy. PLoS ONE, 3 (5). ISSN 19326203 (ISSN)
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Abstract
New developments in fluorophores as well as in detection methods have fueled the rapid growth of optical imaging in the life sciences. Commercial widefield microscopes generally use arc lamps, excitation/ emission filters and shutters for fluorescence imaging. These components can be expensive, difficult to maintain and preclude stable illumination. Here, we describe methods to construct inexpensive and easy-to-use light sources for optical microscopy using light-emitting diodes (LEDs). We also provide examples of its applicability to biological fluorescence imaging. © 2008 Albeanu et al.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | article biomedicine cost effectiveness analysis fluorescence analysis illumination image analysis imaging system light light emitting diode microscopy power supply cost benefit analysis economics instrumentation Cost Benefit Analysis |
| Subjects: | Investigative techniques and equipment Investigative techniques and equipment > optical devices Investigative techniques and equipment > microscopy > immunoflourescence microscopy Investigative techniques and equipment > microscopy |
| CSHL Authors: | |
| Communities: | CSHL labs > Albeanu lab |
| Depositing User: | CSHL Librarian |
| Date: | 2008 |
| Date Deposited: | 19 Mar 2012 20:56 |
| Last Modified: | 04 Dec 2014 16:45 |
| PMCID: | PMC2361193 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/25444 |
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