Gene discovery in Drosophila: new insights for learning and memory

Dubnau, J. T., Tully, T. (March 1998) Gene discovery in Drosophila: new insights for learning and memory. Annual Review of Neuroscience, 21. pp. 407-44. ISSN 0147-006X

DOI: 10.1146/annurev.neuro.21.1.407


Genetic approaches have been used to investigate increasingly complex biological systems. Here we review the current state of genetic analysis of learning and memory in the fruitfly, Drosophila melanogaster. Emerging findings support two main themes. First, discovery and manipulation of genes involved with behavioral plasticity in genetically accessible systems such as D. melanogaster enables dissection of the biochemical, cellular, anatomical, and behavioral pathways of learning and memory. Second, because core cellular mechanisms of simple forms of learning are evolutionarily conserved, biological pathways discovered in invertebrates are likely to be conserved in vertebrate systems as well.

Item Type: Paper
Uncontrolled Keywords: Animals Drosophila melanogaster genetics Genes Insect physiology Learning physiology Memory physiology
Subjects: organism description > animal > insect > Drosophila
organism description > animal behavior > learning
organism description > animal behavior > memory
CSHL Authors:
Communities: CSHL labs > Dubnau lab
CSHL labs > Tully lab
Depositing User: Brian Soldo
Date: March 1998
Date Deposited: 22 Mar 2012 19:09
Last Modified: 09 Apr 2013 16:37
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