Chipping away at brain function: mining for insights with microarrays

Henry, G. L., Zito, K., Dubnau, J. T. (October 2003) Chipping away at brain function: mining for insights with microarrays. Current Opinion in Neurobiology, 13 (5). pp. 570-576. ISSN 0959-4388

DOI: 10.1016/S0959-4388(03)00107-7


The impact of microarray studies on neurobiology has been limited because, with the exception of a few outstanding papers, most reports provide little more than lists of genes, often leaving the reader at a loss to understand which and how many of the identified transcripts will be true positives with significant biological impact. However, some recent papers have offered considerable biological insight by providing independent in vivo confirmation of the roles of candidate genes, offering a glimpse of the potential power of microarrays in neurobiological research.

Item Type: Paper
Uncontrolled Keywords: CIRCADIAN GENE-EXPRESSION Circadian gene expression LONG TERM MEMORY Long term memory HUNTINGTONS DISEASE Huntingtons disease DROSOPHILA MELANOGASTER Drosophila melanogaster MOUSE MODELS Mouse models STEM CELLS Stem cells TRANSCRIPTION Transcription HIPPOCAMPUS Hippocampus PROFILES Profiles IDENTIFICATION Identification
Subjects: bioinformatics > genomics and proteomics > analysis and processing > microarray gene expression processing
organism description > animal behavior > memory
CSHL Authors:
Communities: CSHL labs > Dubnau lab
Depositing User: Brian Soldo
Date: October 2003
Date Deposited: 23 Mar 2012 14:13
Last Modified: 09 Apr 2013 15:42
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