Comparison of DNA replication in cells from prokarya and eukarya

Stillman, B. (1996) Comparison of DNA replication in cells from prokarya and eukarya. In: DNA replication in eukaryotic cells. Cold Spring Harbor monograph series, 31 . Cold Spring Harbor Laboratory Press, Plainview, NY, pp. 435-460. ISBN 0879694599

DOI: 10.1101/087969459.31.435


It is now supposed that utilization of DNA as genetic material emerged after an RNA world existed (Gesteland and Atkins 1993) and that all contemporary organisms evolved from a common ancestor related to primitive photosynthetic bacteria (Woese and Pace 1993). It is therefore not surprising that cells in the three major kingdoms, Bacteria, Archaea, and Eukarya, use roughly similar strategies and mechanisms for genome duplication. Nevertheless, the diversity of DNA replication is evident when the varied strategies used for replication of bacteriophage, plasmid, and virus genomes in both prokaryotes and eukaryotes are considered. This diversity becomes obvious when scanning the chapters that summarize the replication of virus genomes later in this book (Hassell and Brinton; Stenlund; Hay; Challberg; Yates; Traktman; Cotmore and Tattersall; Seeger and Mason; Bisaro; Ahrens et al.). I do not attempt to review these varied mechanisms here but rather focus on comparing the replication of cellular DNA in bacteria and eukaryotes. Unfortunately, except for some studies on DNA polymerases, little is known about the process of DNA replication in Archaea, and therefore inclusion of this kingdom adds little to the discussion.

Item Type: Book Section
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA replication
CSHL Authors:
Communities: CSHL labs > Stillman lab
Highlight: Stillman, Bruce W.
Depositing User: CSHL Librarian
Date: 1996
Date Deposited: 29 Feb 2012 15:01
Last Modified: 20 Jun 2017 14:51

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