Genomics and proteomics approaches in understanding tumor angiogenesis

Mittal, V., Nolan, D. J. (March 2007) Genomics and proteomics approaches in understanding tumor angiogenesis. Expert Rev Mol Diagn, 7 (2). pp. 133-147. ISSN 1744-8352 (Electronic)

DOI: 10.1586/14737159.7.2.133


Functional genomic and proteomic approaches have begun to revolutionize cancer research. The advent of powerful technologies, such as DNA microarrays, serial analysis of gene expression, RNA interference and proteomics, has accelerated investigations of gene identification and function at a scale never before accomplished. Approaches integrating these technologies with high-throughput forward and reverse genetic screens, are already providing insights into the mechanistic understanding of angiogenesis, leading to the identification of proteins that can be used for selective targeting of tumor vessels.

Item Type: Paper
Subjects: diseases & disorders > cancer
Investigative techniques and equipment
bioinformatics > genomics and proteomics > Validation and Standardization > Microarray Data Standardization and Validation
bioinformatics > genomics and proteomics > analysis and processing > microarray gene expression processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi
diseases & disorders > cancer > angiogenesis
CSHL Authors:
Communities: CSHL labs > Mittal lab
Depositing User: CSHL Librarian
Date: March 2007
Date Deposited: 10 Nov 2011 14:59
Last Modified: 02 Apr 2018 19:31
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