High-resolution ROMA analysis of chromosomal rearrangements in mesothelioma patients with poor and good survival

Ivanov, S. V., Ivanova, A. V., Lucito, R., Pass, H. I. (August 2007) High-resolution ROMA analysis of chromosomal rearrangements in mesothelioma patients with poor and good survival. Journal of Thoracic Oncology, 2 (8). S431-S431. ISSN 1556-0864

Abstract

Representational oligonucleotide microarray analysis (ROMA) is a recently developed microarray-based high-resolution technology that helps linking chromosomal losses and gains with specific genetic events. ROMA identifies the boundaries of deletions, duplications, and amplifications with the accuracy of roughly 50-100 kb throughout the whole human genome. Mesothelioma is an aggressive asbestos-related cancer with short (median 11-22 months) survival and poorly investigated genetic components.

Item Type: Paper
Additional Information: Meeting Abstract
Subjects: diseases & disorders > cancer
Investigative techniques and equipment > ROMA
Publication Type > Meeting Abstract
diseases & disorders > cancer > cancer types > mesothelioma
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > oligonucleotide
CSHL Authors:
Communities: CSHL labs > Lucito lab
Depositing User: CSHL Librarian
Date: August 2007
Date Deposited: 14 Nov 2011 19:20
Last Modified: 27 Mar 2018 19:39
URI: https://repository.cshl.edu/id/eprint/23049

Actions (login required)

Administrator's edit/view item Administrator's edit/view item