Duelli, D., Lazebnik, Y. (December 2007) Cell-to-cell fusion as a link between viruses and cancer. Nat Rev Cancer, 7 (12). pp. 968-76. ISSN 1474-1768 (Electronic)
Abstract
The ability to fuse cells is shared by many viruses, including common human pathogens and several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer, what types of cancers it can affect, how the existence of this link can be tested and how the hypotheses that we propose might affect the search for human oncogenic viruses. In particular, we will focus on the ability of cell fusion that is caused by viruses to induce chromosomal instability, a common affliction of cancer cells that has been thought to underlie the malignant properties of cancerous tumours.
| Item Type: | Paper |
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| Additional Information: | |
| Subjects: | diseases & disorders > cancer Investigative techniques and equipment > cell fusion organism description > virus |
| CSHL Authors: | |
| Communities: | CSHL labs > Labeznik lab |
| Depositing User: | CSHL Librarian |
| Date: | December 2007 |
| Date Deposited: | 30 Nov 2011 21:03 |
| Last Modified: | 22 Mar 2018 18:41 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/23003 |
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