Huang, Z. J. (May 2006) GABAB receptor isoforms caught in action at the scene. Neuron, 50 (4). pp. 521-4. ISSN 0896-6273 (Print)
Abstract
The metabotropic GABAB receptors mediate slow synaptic inhibition and consist of heterodimers of GABAB1 and GABAB2 subunits. The only known molecular diversity of the GABAB receptors arises from the two GABAB1 isoforms, but its functional significance has been unclear. Two studies in this issue of Neuron now demonstrate that GABAB1a and GABAB1b show strategically distinct subcellular localization and physiological action.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Brain physiology Humans Neurons metabolism Protein Isoforms physiology Receptors GABA-B physiology |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics > heterochromatin bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein receptor organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions > synapse |
| CSHL Authors: | |
| Communities: | CSHL labs > Huang lab |
| Depositing User: | CSHL Librarian |
| Date: | 18 May 2006 |
| Date Deposited: | 14 Dec 2011 15:17 |
| Last Modified: | 10 Jan 2017 17:00 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/22825 |
Actions (login required)
 |
Administrator's edit/view item |