Xuan, Z. Y., Zhao, F., Wang, J., Chen, G., Zhang, M. Q. (2005) Genome-wide promoter extraction and analysis in human, mouse, and rat. Genome Biology, 6 (8). R72. ISSN 1465-6906
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Abstract
Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter prediction by incorporating both transcript and conservation information. This enabled us to build a better multispecies promoter annotation pipeline and hence to create CSHLmpd (Cold Spring Harbor Laboratory Mammalian Promoter Database) for the biomedical research community, which can act as a starting reference system for more refined functional annotations.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Conserved Sequence genetics CpG Islands genetics Databases Genetic Gene Expression Regulation Genome genetics Genome Human genetics Humans Mice Oligonucleotide Array Sequence Analysis Promoter Regions genetics RNA Messenger genetics metabolism Rats Research Design Sensitivity and Specificity Species Specificity User-Computer Interface |
| Subjects: | bioinformatics > genomics and proteomics > annotation bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription bioinformatics > genomics and proteomics > databases > database optimization bioinformatics > genomics and proteomics > databases bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA expression > promoter |
| CSHL Authors: | |
| Communities: | CSHL labs > Zheng lab |
| Depositing User: | CSHL Librarian |
| Date: | 2005 |
| Date Deposited: | 21 Dec 2011 17:18 |
| Last Modified: | 21 Dec 2011 17:18 |
| URI: | https://repository.cshl.edu/id/eprint/22738 |
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