Kim, J. Y., Rim, Y., Wang, L., Jackson, D. P. (April 2005) A novel cell-to-cell trafficking assay indicates that the KNOX homeodomain is necessary and sufficient for intercellular protein and mRNA trafficking. Genes & Development, 19 (7). pp. 788-793. ISSN 0890-9369
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Abstract
Cell-to-cell trafficking of regulatory proteins is a novel mechanism for communication during cell fate specification in plants. Although several developmental proteins traffic cell-to-cell, no signals that are both necessary and sufficient for this function in developmental proteins have been described. We developed a novel trafficking assay using trichome rescue in Arabidopsis. Fusion to KNOTTED1 (KN1) conferred gain-of-trafficking function to the cell-autonomous GLABROUS1 (GL1) protein. We show that the KNOX homeodomain (HD) is necessary and sufficient for intercellular trafficking, identifying a novel function for the HD as the minimal sequence required for trafficking of KN1 and its associated mRNA.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | KNOX homeodomain trichome trafficking signal Glabrous 1 knotted1 tobacco mosaic virus movement protein shoot meristem homeobox gene selective trafficking Arabidopsis expression plants maize leaf |
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell functions |
| CSHL Authors: | |
| Communities: | CSHL labs > Jackson lab |
| Depositing User: | CSHL Librarian |
| Date: | April 2005 |
| Date Deposited: | 12 Jan 2012 17:12 |
| Last Modified: | 11 Jan 2017 21:27 |
| PMCID: | PMC1074316 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/22622 |
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