Markram, H., Toledo-Rodriguez, M., Wang, Y., Gupta, A., Silberberg, G., Wu, C. Z.
(October 2004)
Interneurons of the neocortical inhibitory system.
Nature Reviews Neuroscience, 5 (10).
pp. 793-807.
ISSN 1471-0048
Abstract
Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions that are supported by the neocortex. The neocortex, which forms almost 80% of the human brain, seems to have arisen from repeated duplication of a stereotypical microcircuit template with subtle specializations for different brain regions and species. The quest to unravel the blueprint of this template started more than a century ago and has revealed an immensely intricate design. The largest obstacle is the daunting variety of inhibitory interneurons that are found in the circuit. This review focuses on the organizing principles that govern the diversity of inhibitory interneurons and their circuits.
| Item Type: |
Paper
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| Uncontrolled Keywords: |
CAT VISUAL-CORTEX
cat visual cortex
RAT FRONTAL-CORTEX
rat frontal cortex
DUAL INTRACELLULAR-RECORDINGS
dual intracellular recordings
EXCITATORY POSTSYNAPTIC POTENTIALS
excitatory postsynaptic potentials
GLUTAMATE-RECEPTOR CHANNELS
glutamate receptor channels
GOLGI-ELECTRON MICROSCOPE
golgi-electron microscope
GABAERGIC CELL SUBTYPES
GABAergic cell subtypes
SYNAPTIC RELEASE
synaptic release
SITES
sites
MONKEY CEREBRAL-CORTEX
monkey cerebral cortex
SINGLE PYRAMIDAL CELLS
single pyramidal cells |
| Subjects: |
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neocortical interneurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neocortical interneurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neocortical interneurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neocortical interneurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neocortical interneurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neocortical interneurons |
| CSHL Authors: |
|
| Depositing User: |
CSHL Librarian
|
| Date: |
October 2004 |
| Date Deposited: |
01 Feb 2012 15:21 |
| Last Modified: |
01 Feb 2012 15:21 |
| URI: |
https://repository.cshl.edu/id/eprint/22433 |
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