Speck, N. A., Vakoc, C. R. (June 2010) PAF Is in the Cabal of MLL1-Interacting Proteins that Promote Leukemia. Cancer Cell, 17 (6). pp. 531-532.
Abstract
MLL1 fusions are among the most potent oncogenic drivers of leukemia development. In recent articles published in Molecular Cell and in Cancer Cell, researchers find that MLL1 fusions are reliant on a physical interaction with the PAF transcription elongation complex for their recruitment to chromatin and, consequently, leukemic transformation. © 2010 Elsevier Inc. All rights reserved.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > cancer bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription diseases & disorders diseases & disorders > cancer > cancer types > leukemia diseases & disorders > cancer > cancer types |
| CSHL Authors: | |
| Communities: | CSHL labs > Vakoc lab |
| Depositing User: | CSHL Librarian |
| Date: | 15 June 2010 |
| Date Deposited: | 19 Oct 2011 14:47 |
| Last Modified: | 13 Mar 2013 20:07 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/15533 |
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