Browse by CSHL Author

Moon, S. H., Huang, C. H., Houlihan, S. L., Regunath, K., Freed-Pastor, W. A., Morris, J. P. th, Tschaharganeh, D. F., Kastenhuber, E. R., Barsotti, A. M., Culp-Hill, R., Xue, W., Ho, Y. J., Baslan, T., Li, X., Mayle, A., de Stanchina, E., Zender, L., Tong, D. R., D'Alessandro, A., Lowe, S. W., Prives, C. (December 2018) p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell, 176 (3). pp. 564-580. ISSN 0092-8674

Li, J., Chanrion, M., Sawey, E., Wang, T., Chow, E., Tward, A., Su, Y., Xue, W., Lucito, R., Zender, L., Lowe, S. W., Bishop, J. M., Powers, S. (March 2015) Reciprocal Interaction of Wnt and RXR-alpha Pathways in Hepatocyte Development and Hepatocellular Carcinoma. PLoS One, 10 (3). e0118480. ISSN 1932-6203

Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C. H., Lechel, A., Andersen, J. B., Capper, D., Zender, L., Longerich, T., Enikolopov, G., Lowe, S. W. (July 2014) p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer. Cell, 158 (3). pp. 579-92. ISSN 0092-8674

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, A. R., Simon, J., Zhang, J., Luo, W. J., Hicks, J., Zender, L., Wang, X. W., Powers, S., Wigler, M., Lowe, S. W. (May 2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8212-8217. ISSN 0027-8424

Liu, L. X., Lee, N. P. , Chan, V. W. , Xue, W., Zender, L., Zhang, C., Mao, M., Dai, H., Wang, X. L., Xu, M. Z. , Lee, T. K. , Ng, I. O. , Chen, Y., Kung, H.-f. , Lowe, S. W. , Poon, R. T. P. , Wang, J. H., Luk, J. M. (November 2009) Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology, 50 (5). pp. 1453-1463. ISSN 1527-3350

Zender, L., Xue, W., Zuber, J., Semighini, C. P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J. M., Schirmacher, P., McCombie, W. R., Wigler, M. H., Hicks, J. B., Hannon, G. J., Powers, S., Lowe, S. W. (November 2008) An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer. Cell, 135 (5). pp. 852-864. ISSN 0092-8674

Gyrd-Hansen, M., Darding, M., Miasari, M., Santoro, M. M., Zender, L., Xue, W., Tenev, T., da Fonseca, P. C., Zvelebil, M., Bujnicki, J. M., Lowe, S. W., Silke, J., Meier, P. (November 2008) IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat Cell Biol, 10 (11). pp. 1309-17.

Burgess, D. J., Doles, J., Zender, L., Xue, W., Ma, B., McCombie, W. R., Hannon, G. J., Lowe, S. W., Hemann, M. T. (July 2008) Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A, 105 (25). pp. 9053-9058.

Xue, W., Krasnitz, A., Lucito, R., Sordella, R., Van Aelst, L., Cordon-Cardo, C., Singer, S., Kuehnel, F., Wigler, M. H., Powers, S., Zender, L., Lowe, S. W. (June 2008) DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development, 22 (11). pp. 1439-44. ISSN 0890-9369

Krizhanovsky, V., Xue, W., Zender, L., Yon, M., Hernando, E., Lowe, S. W. (2008) Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology. Cold Spring Harb Symp Quant Biol, 73. pp. 513-22.

Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C., Lowe, S. W. (February 2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature, 445 (7128). pp. 656-660. ISSN 0028-0836

Zender, L., Xue, W., Cordon-Cardo, C., Lowe, S. W. (October 2006) P53 restoration in liver carcinomas induces cellular senescence and tumor clearance through an innate immune response. Hepatology, 44 (4). 694A-695A. ISSN 0270-9139

Lakshmi, B., Hall, I. M., Egan, C., Alexander, J., Leotta, A., Healy, J., Zender, L., Spector, M. S., Xue, W., Lowe, S. W., Wigler, M. H., Lucito, R. (July 2006) Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens. Proc Natl Acad Sci U S A, 103 (30). pp. 11234-9. ISSN 0027-8424 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M. H., Hannon, G. J., Mu, D., Lucito, R., Powers, S., Lowe, S. W. (June 2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell, 125 (7). pp. 1253-67. ISSN 0092-8674 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Mu, D., Cordon-Cardo, C., Powers, S., Hannon, G. J., Lucito, R., Lowe, S. W. (October 2005) Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma. Hepatology, 42 (4). 244A-244A. ISSN 0270-9139

Zender, L., Xue, W., Cordon-Cardo, C., Hannon, G. J., Lucito, R., Powers, S., Flemming, P., Spector, M. S., Lowe, S. W. (2005) Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors. Cold Spring Harb Symp Quant Biol, 70 (1). pp. 251-261. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)