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Number of items at this level: 11.

Paper

Brenner, M., Münch, J., Schindler, M., Wildum, S., Stolte, N., Stahl-Hennig, C., Fuchs, D., Mätz-Rensing, K., Franz, M., Heeney, J. L., Ten Haaft, P., Swigut, T., Hrecka, K., Skowronski, J., Kirchhoff, F. (May 2006) Importance of the N-distal AP-2 binding element in Nef for simian immunodeficiency virus replication and pathogenicity in rhesus macaques. Journal of Virology, 80 (9). pp. 4469-4481. ISSN 0022538X

Hrecka, K., Swigut, T., Schindler, M., Kirchhoff, F., Skowronski, J. (August 2005) Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1. J Virol, 79 (16). pp. 10650-9. ISSN 0022-538X (Print)

Swigut, T., Alexander, L., Morgan, J., Lifson, J., Mansfield, K. G., Lang, S., Johnson, R. P., Skowronski, J., Desrosiers, R. (December 2004) Impact of nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus. Journal of Virology, 78 (23). pp. 13335-13344. ISSN 0022-538X

Janardhan, A., Swigut, T., Hill, B., Myers, M. P., Skowronski, J. (January 2004) HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol, 2 (1). E6. ISSN 1545-7885 (Electronic)

Stove, V., Naessens, E., Stove, C., Swigut, T., Plum, J., Verhasselt, B. (October 2003) Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development. Blood, 102 (8). pp. 2925-2932. ISSN 0006-4971

Swigut, T., Greenberg, M., Skowronski, J. (July 2003) Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis. Journal of Virology, 77 (14). pp. 8116-8126. ISSN 0022-538X

Munch, J., Janardhan, A., Stolte, N., Stahl-Hennig, C., ten Haaft, P., Heeney, J. L., Swigut, T., Kirchhoff, F., Skowronski, J. (December 2002) T-Cell Receptor : CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques. Journal of Virology, 76 (23). pp. 12360-12364. ISSN 0022-538X

Swigut, T., Shohdy, N., Skowronski, J. (April 2001) Mechanism for down-regulation of CD28 by Nef. Embo Journal, 20 (7). pp. 1593-1604. ISSN 0261-4189

Iafrate, A. J., Carl, S., Bronson, S., Stahl-Hennig, C., Swigut, T., Skowronski, J., Kirchhoff, F. (November 2000) Disrupting surfaces of Nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo. Journal of Virology, 74 (21). pp. 9836-9844. ISSN 0022-538X

Lock, M., Greenberg, M. E., Iafrate, A. J., Swigut, T., Muench, J., Kirchhoff, F., Shohdy, N., Skowronski, J. (May 1999) Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. Embo Journal, 18 (10). pp. 2722-33. ISSN 0261-4189 (Print)

Skowronski, J., Greenberg, M. E., Lock, M., Mariani, R., Salghetti, S., Swigut, T., Iafrate, A. J. (1999) HIV and SIV Nef modulate signal transduction and protein sorting in T cells. Cold Spring Harb Symp Quant Biol, 64. pp. 453-63. ISSN 0091-7451 (Print)

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