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Paper

Romero-Hernandez, Annabel, Simorowski, Noriko, Karakas, Erkan, Furukawa, Hiro (December 2016) Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Neuron, 92 (6). pp. 1324-1336. ISSN 0896-6273 (Public Dataset)

Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H. (May 2016) Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature, 534 (7605). pp. 63-8. ISSN 1476-4687 (Electronic)0028-0836 (Linking) (Public Dataset)

Karakas, Erkan, Regan, Michael C., Furukawa, Hiro (June 2015) Emerging structural insights into the function of ionotropic glutamate receptors. Trends in Biochemical Sciences, 40 (6). pp. 328-337. ISSN 0968-0004

Khatri, A., Burger, P. B., Swanger, S. A., Hansen, K. B., Zimmerman, S., Karakas, E., Liotta, D. C., Furukawa, H., Snyder, J. P., Traynelis, S. F. (September 2014) Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator. Mol Pharmacol, 86 (5). pp. 548-560. ISSN 0026-895x

Karakas, E., Furukawa, H. (May 2014) Crystal structure of a heterotetrameric NMDA receptor ion channel. Science, 344 (6187). pp. 992-7. ISSN 1095-9203 (Electronic)0036-8075 (Linking) (Public Dataset)

Burger, P. B., Yuan, H. J., Karakas, E., Geballe, M., Furukawa, H., Liotta, D. C., Snyder, J. P., Traynelis, S. F. (August 2012) Mapping the Binding of GluN2B-Selective N-Methyl-D-aspartate Receptor Negative Allosteric Modulators. Molecular Pharmacology, 82 (2). pp. 344-359. ISSN 0026-895X

Karakas, E., Simorowski, N., Furukawa, H. (July 2011) Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature, 475 (7355). 249- U170. ISSN 00280836 (Public Dataset)

Karakas, Erkan, Simorowski, Noriko, Furukawa, Hiro (January 2010) Structural Insights into Allosteric Modulation of NMDA Receptors Through the Amino-Terminal Domain. Biophysical Journal, 98 (3, Sup). 609a-609a.

Karakas, E., Simorowski, N., Furukawa, H. (November 2009) Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. Embo Journal, 28 (24). pp. 3910-3920. ISSN 0261-4189 (Public Dataset)

Patent

Hiro Furukawa (February 2014) Phenylethanolamine-based NMDA receptor antagonists. United States Patent 8648198. .