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Dasgupta, A., Shukla, S.K., Vernucci, E., King, R.J., Abrego, J., Mulder, S.E., Mullen, N.J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K.S., Wang, D., Chaika, N.V., Pacheco, C.G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B.N., Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K.A., Hollingsworth, M.A., Zimmerman, M.C., Mehla, K., Sadoshima, J., Tuveson, D. A., Singh, P.K. (July 2020) SIRT1-NOX4 Signaling Axis Regulates Cancer Cachexia. J Exp Med, 217 (7). e20190745. ISSN 0022-1007

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Da Silva, B., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grutzmann, R., Aust, D., Gimotty, P. A., Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A., Tuveson, D. A. (June 2019) The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science, 364 (6446). pp. 1156-1162. ISSN 0036-8075

Elyada, E., Bolisetty, M., Laise, P., Flynn, W. F., Courtois, E. T., Burkhart, R. A., Teinor, J. A., Belleau, P., Biffi, G., Lucito, M. S., Sivajothi, S., Armstrong, T. D., Engle, D. D., Yu, K. H., Hao, Y., Wolfgang, C. L., Park, Y., Preall, J., Jaffee, E. M., Califano, A., Robson, P., Tuveson, D. A. (June 2019) Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. Cancer Discov, 9 (8). pp. 1102-1123. ISSN 2159-8274

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Engle, D., Tiriac, H., Pommier, A., Schoepfer, C., Da Silva, B., Yao, M., Park, Y., Hollingsworth, M. A., Tuveson, D. (May 2018) Exploring the role of glycosylation in pancreatic diseass. Cancer Research, 78 (10 Sup). p. 44. ISSN 0008-5472

Tuveson, D., Engle, D., Hwang, C., Vakoc, C., Roe, J. S. (May 2018) GEMMs and GEOs to characterize pancreatic cancer initiation and progression. Cancer Research. ISSN 0008-5472

Tiriac, H., Burkhart, R. A., Belleau, P., Young, M. C., Ma, M., Engle, D. D., Li, E., Yu, K. H., Tuveson, D. A. (May 2018) Pharmacotyping patients using pancreatic cancer organoids. Cancer Research, 78 (10, Su). ISSN 0008-5472

Wolff, R. A., Wang-Gillam, A., Alvarez, H., Tiriac, H., Engle, D., Hou, S., Groff, A. F., Lucas, A. S., Bernard, V., Allenson, K., Castillo, J., Kim, D., Mulu, F., Huang, J., Stephens, B., Wistuba, I. I., Katz, M., Varadhachary, G., Park, Y., Hicks, J., Chinnaiyan, A., Scampavia, L., Spicer, T., Gerhardinger, C., Maitra, A., Tuveson, D., Rinn, J., Lizee, G., Yee, C., Levine, A. J. (March 2018) Dynamic changes during the treatment of pancreatic cancer. Oncotarget, 9 (19). pp. 14764-14790. ISSN 1949-2553

Ohlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., Chio, II, Hwang, C. I., Tiriac, H., Baker, L. A., Engle, D. D., Feig, C., Kultti, A., Egeblad, M., Fearon, D. T., Crawford, J. M., Clevers, H., Park, Y., Tuveson, D. A. (March 2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med, 214 (3). pp. 579-596. ISSN 0022-1007

Ireland, L., Santos, A., Ahmed, M. S., Rainer, C., Nielsen, S. R., Quaranta, V., Weyer-Czernilofsky, U., Engle, D. D., Perez-Mancera, P., Coupland, S. E., Taktak, A. F., Bogenrieder, T., Tuveson, D. A., Campbell, F., Schmid, M. C., Mielgo, A. (December 2016) Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Res, 76 (23). pp. 6851-6863. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Nielsen, S. R., Quaranta, V., Linford, A., Emeagi, P., Rainer, C., Santos, A., Ireland, L., Sakai, T., Sakai, K., Kim, Y. S., Engle, D., Campbell, F., Palmer, D., Ko, J. H., Tuveson, D. A., Hirsch, E., Mielgo, A., Schmid, M. C. (April 2016) Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nat Cell Biol, 18 (5). pp. 549-60. ISSN 1476-4679 (Electronic)1465-7392 (Linking)

Seifert, L., Werba, G., Tiwari, S., Giao Ly, N. N., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S. H., Torres-Hernandez, A., Pergamo, M., Ochi, A., Zambirinis, C. P., Pansari, M., Rendon, M., Tippens, D., Hundeyin, M., Mani, V. R., Hajdu, C., Engle, D., Miller, G. (April 2016) The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature, 532 (7598). pp. 245-9. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Boj, S. F., Hwang, C. I., Baker, L. A., Engle, D. D., Tuveson, D. A., Clevers, H. (January 2016) Model organoids provide new research opportunities for ductal pancreatic cancer. Mol Cell Oncol, 3 (1). e1014757. ISSN 2372-3556 (Electronic)2372-3556 (Linking)

Zambirinis, C. P., Levie, E., Nguy, S., Avanzi, A., Barilla, R., Xu, Y., Seifert, L., Daley, D., Greco, S. H., Deutsch, M., Jonnadula, S., Torres-Hernandez, A., Tippens, D., Pushalkar, S., Eisenthal, A., Saxena, D., Ahn, J., Hajdu, C., Engle, D. D., Tuveson, D., Miller, G. (October 2015) TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Roy, I., McAllister, D. M., Gorse, E., Dixon, K., Piper, C. T., Zimmerman, N. P., Getschman, A. E., Tsai, S., Engle, D. D., Evans, D. B., Volkman, B. F., Kalyanaraman, B., Dwinell, M. B. (September 2015) Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling. Cancer Res, 75 (17). pp. 3529-42. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Roy, I., McAllister, D., Gorse, E., Dixon, K., Cheng, G., Getschman, A., Engle, D., Tsai, S., Tuveson, D., Evans, D., Volkman, B., Kalyanaraman, B., Dwinell, M. (July 2015) Chemokine biased agonists regulate pancreatic cancer migration and metastasis through bioenergetic signaling. Cancer Research, 75 (Supple). B55. ISSN 0008-5472

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H M., Molenaar, I.  Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert G J., Clevers, Hans, Tuveson, David A (January 2015) Organoid Models of Human and Mouse Ductal Pancreatic Cancer. Cell, 160 (1-2). pp. 324-338. ISSN 0092-8674

Naguib, A., Bencze, G., Engle, D. D., Chio, II, Herzka, T., Watrud, K., Bencze, S., Tuveson, D. A., Pappin, D. J., Trotman, L. C. (December 2014) P53 Mutations Change Phosphatidylinositol Acyl Chain Composition. Cell Reports, 10 (1). pp. 8-19. ISSN 2211-1247

Ponz-Sarvise, M., Corbo, V., Ohlund, D., Oni, T., Handly-Santana, A., Engle, D., Tiriac, H., Chio, C., Feigin, M., Baker, L., Ardito-Abraham, C., Park, Y., Hwang, C., Elyada, E., Yu, K., Clevers, H., Tuveson, D. A. (November 2014) Pancreatic ductal organoids as a new platform for drug discovery. European Journal of Cancer, 50. p. 63. ISSN 0959-8049

Sherman, Mara H, Yu, Ruth T, Engle, Dannielle D, Ding, Ning, Atkins, Annette R, Tiriac, Herve, Collisson, Eric A, Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W, Dawson, David W, Donahue, Timothy R, Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V, Wilson, Jeremy S, Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E, Wahl, Geoffrey M, Hunter, Tony, Drebin, Jeffrey A, O’Dwyer, Peter J, Liddle, Christopher, Tuveson, David A, Downes, Michael, Evans, Ronald M (September 2014) Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell, 159 (1). pp. 80-93. ISSN 0092-8674