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Paper

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda, Tuveson, David A (May 2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of USA, 118 (21). e2016904118-e2016904118. ISSN 0027-8424

Cheng, D. K., Oni, T. E., Park, Y., Thalappillil, J. S, Ting, H.-C., Alagesan, B., Prasad, N. V., Rivera, K. D., Pappin, D. J., Van Aelst, L., Tuveson, D. A. (September 2020) Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer. BioRxiv. (Unpublished)

Humpton, T. J., Alagesan, B., DeNicola, G. M., Lu, D., Yordanov, G. N., Leonhardt, C. S., Yao, M. A., Alagesan, P., Zaatari, M. N., Park, Y., Skepper, J. N., Macleod, K. F., Perez-Mancera, P. A., Murphy, M. P., Evan, G. I., Vousden, K. H., Tuveson, D. A. (July 2019) Oncogenic Kras induces Nix-mediated mitophagy to promote pancreatic cancer. Cancer Discov, 99 (9). pp. 1268-1298. ISSN 2159-8274

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Da Silva, B., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grutzmann, R., Aust, D., Gimotty, P. A., Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A., Tuveson, D. A. (June 2019) The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science, 364 (6446). pp. 1156-1162. ISSN 0036-8075

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H M., Molenaar, I.  Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert G J., Clevers, Hans, Tuveson, David A (January 2015) Organoid Models of Human and Mouse Ductal Pancreatic Cancer. Cell, 160 (1-2). pp. 324-338. ISSN 0092-8674

Conference or Workshop Item

Caligiuri, Giuseppina, Thalappillil, Jennifer S, Shakiba, Mojdeh, Nadella, Sandeep, Hinds, Juliene, Courtois, Elise, Flynn, William F, Alagesan, Brinda, Yordanov, Georgi N, Kaminow, Benjamin, Robson, Paul, Perez-Mancera, Pedro A, Preall, Jonathan, Dobin, Alexander, Park, Youngku, Tuveson, David A (2022) Oncogenic KRAS signaling drives the activation of tissue-resident fibroblasts and is required to maintain CAF heterogeneity in pancreatic cancer. In: AACR Special Conference on Pancreatic Cancer, 2022 Sep 13-16, Boston, MA.

Thalappillil, Jennifer S, Caligiuri, Giuseppina, Nadella, Sandeep, Alagesan, Brinda, Yordanov, Georgi N, Shakiba, Mojdeh, Kaminow, Benjamin, Hinds, Juliene, Perez-Mancera, Pedro A, Preall, Jonathan, Dobin, Alexander, Park, Youngkyu, Tuveson, David A (2022) Oncogenic Kras drives cancer-associated fibroblast heterogeneity and substate changes in pancreatic cancer. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.