Meeting Report: Can We Make Animal Models of Human Mental Illness?

Monteggia, Lisa, Heimer, Hakon, Nestler, Eric J. (October 2018) Meeting Report: Can We Make Animal Models of Human Mental Illness? Biological Psychiatry, 84 (7). pp. 541-545. ISSN 0006-3223

DOI: 10.1016/j.biopsych.2018.02.010


Modeling aspects of the human condition in animals has provided invaluable information on the physiology of all organ systems as well as assisted in the development of virtually all new therapeutics. Research in cardiovascular disease, cancer, immunology, and others has benefited substantially from the availability of animal models that capture aspects of specific human diseases and that have been used effectively to advance new treatments. By comparison, animal models for neurological and psychiatric disorders have faced several unique obstacles. This essay highlights topics covered in a recent Cold Spring Harbor Laboratory meeting charged with examining the status of animal models for mental illness. The consensus of the conference is that, despite the difficulties inherent with modeling brain disorders in animals, when used judiciously�fully cognizant that models of specific behavioral or biological aspects cannot completely recapitulate the human disorder, animal research is crucial for advancing our understanding of neuropsychiatric disease.

Item Type: Paper
Subjects: diseases & disorders
diseases & disorders > mental disorders
organism description > animal
CSHL Authors:
Communities: Banbury Center
Depositing User: Matthew Dunn
Date: 1 October 2018
Date Deposited: 18 Sep 2018 18:20
Last Modified: 18 Sep 2018 18:20
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