Metabolic differences between two transmission lines of mouse leukemia

Victor, Joseph, Potter, James S. (1933) Metabolic differences between two transmission lines of mouse leukemia. Proceedings of the Society for Experimental Biology and Medicine, 30. pp. 532-534.

DOI: 10.3181/00379727-30-6557


The experiments of Warburg1 on the metabolic differences between tumors and normal tissues have stimulated similar investigations in leukemia. Although considerable data have accumulated relative to the metabolism of the cells in leukemia, many of the conclusions have been contradictory. The following investigation has been undertaken as part of the program conducted in these laboratories in which the genetics, pathology and cytology of transmissible leukemia of mice have been reported by MacDowell, Richter and Potter.2 The genetically controlled material developed in their studies is particularly suitable for metabolic experiments. The oxygen consumption and both aerobic and anaerobic glycolysis of normal lymph nodes and leukemic lymph nodes of 2 distinct transmission lines, designated A and I, have been studied by one of us.

Item Type: Paper
Subjects: diseases & disorders > cancer > cancer types > leukemia
organism description > animal > mammal > rodent > mouse
Communities: The Carnegie Institution Department of Genetics
Depositing User: Elizabeth Pessala
Date: 1933
Date Deposited: 08 May 2017 19:12
Last Modified: 08 May 2017 19:12

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