Burridge, K., McCullough, L. (1980) The association of alpha-actinin with the plasma membrane. Journal of Supramolecular Structure, 13 (1). pp. 53-65. ISSN 0091-7419
Abstract
The role of alpha-actinin in the attachment of actin to plasma membranes has been investigated. Specific antibody staining of SDS gels has indicated that alpha-actinin is a major component in isolated plasma membranes prepared from three different cell types by two different procedures. Using specific extraction conditions, most of the alpha-actinin can be selectively extracted from the membranes with relatively little parallel release of actin. This selective dissociation of alpha-actinin from the plasma membrane leads us to conclude that alpha-actinin is present in these membrane preparations, because it is bound to actin, and that alpha-actinin does not form a direct link between actin and the membrane.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > actin organs, tissues, organelles, cell types and functions > tissues types and functions > membranes |
| CSHL Authors: | |
| Communities: | CSHL labs |
| Depositing User: | Matt Covey |
| Date: | 1980 |
| Date Deposited: | 10 Aug 2016 16:12 |
| Last Modified: | 10 Aug 2016 16:12 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/32666 |
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