Caskey, C. T., Gibbs, R. A., Witkowski, J. A., Hejtmancik, J. F. (June 1988) Diagnosis of human heritable defects by recombinant DNA methods. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 319 (1194). pp. 353-60. ISSN 0962-8436 (Print)0962-8436
Abstract
Recombinant DNA methods provide highly sensitive means for the detection of DNA alterations that lead to human disease mutations. In this paper I shall illustrate the approaches currently available and discuss new technologies that show promise of replacing the present methods. Medical diagnosis by means of recombinant DNA methods has an expanding role in clinical medicine.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | *DNA, Recombinant Female Genetic Diseases, Inborn/*diagnosis Genetic Engineering/methods *Genetic Techniques Humans *Mutation Pregnancy Prenatal Diagnosis |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification Investigative techniques and equipment bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > recombination |
| CSHL Authors: | |
| Communities: | Banbury Center |
| Depositing User: | Matt Covey |
| Date: | 15 June 1988 |
| Date Deposited: | 01 Dec 2014 20:42 |
| Last Modified: | 01 Dec 2014 20:42 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/30410 |
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