Transcriptional control and the ubiquitin-proteasome system

Leung, A., Geng, F., Daulny, A., Collins, G. A., Guzzardo, P. M., Tansey, W. P. (2008) Transcriptional control and the ubiquitin-proteasome system. Ernst Schering Found Symp Proc (1). pp. 75-97.

Abstract

Regulation of transcription is a critically important process that controls development, differentiation, and the maintenance of cellular homeostasis. Cells have evolved numerous mechanisms to keep gene transcription tightly in check, some of which involve the ubiquitin-proteasome system. In this chapter, we review evidence supporting the concept that ubiquitin and the proteasome not only control transcription, but provide the biochemical means to drive key steps in the transcription process forward.

Item Type:	Paper
Subjects:	bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > ubiquitin ligase
CSHL Authors:	Tansey, William P. Collins, Galen A. Daulny, Anne Geng, Fuqiang Guzzardo, Paloma M.
Communities:	CSHL labs > Tansey lab School of Biological Sciences > Publications
Depositing User:	Matt Covey
Date:	2008
Date Deposited:	22 Feb 2013 19:20
Last Modified:	22 Sep 2014 16:20
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/27635

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