Tourette's Disorder

Lyon, Gholson J., Shprecher, David, Coffey, Barbara, Kurlan, Roger (2010) Tourette's Disorder. Current Treatment Options in Neurology, 12 (4). pp. 274-286. ISSN 1534-3138

DOI: 10.1007/s11940-010-0073-x


OPINION STATEMENT: Tourette's disorder (TD) is a common childhood-onset neuropsychiatric disorder characterized by chronic motor and vocal tics. TD frequently occurs with other neuropsychiatric disorders, such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD), and may contribute to reduced quality of life and disability. Currently available treatments to reduce tics are limited by variable clinical response and frequent adverse effects. They include alpha-2 agonists, antipsychotics (first and second generation), tetrabenazine, benzodiazepines, and habit reversal therapy. Some new and emerging (but unproven) treatments are also discussed, including topiramate and dopamine agonists. In addition, there is increasing interest in deep brain stimulation, but this is not yet ready for general use.

Item Type: Paper
Subjects: diseases & disorders > mental disorders
CSHL Authors:
Communities: CSHL labs > Lyon lab
Depositing User: Matt Covey
Date: 2010
Date Deposited: 10 Dec 2012 20:14
Last Modified: 10 Dec 2012 21:15

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