Sedman, J., Stenlund, A. (August 1998) The papillomavirus E1 protein forms a DNA-dependent hexameric complex with ATPase and DNA helicase activities. J Virol, 72 (8). pp. 6893-7. ISSN 0022-538X (Print)
Abstract
The E1 protein from bovine papillomavirus has site-specific DNA binding activity, DNA helicase activity, and DNA-dependent ATPase activity consistent with the properties of an initiator protein. Here we have identified and characterized a novel oligomeric form of E1 that is associated with the ATPase and DNA helicase activities and whose formation is strongly stimulated by single-stranded DNA. This oligomeric form corresponds to a hexamer of E1.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Adenosinetriphosphatase metabolism Animals Cattle DNA metabolism DNA Helicases metabolism DNA Single Stranded DNA Binding Proteins metabolism Papillomavirus Bovine metabolism Research Support US Govt PHS Viral Proteins metabolism |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA expression bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > helicase |
| CSHL Authors: | |
| Communities: | CSHL labs > Stenlund lab |
| Depositing User: | Brian Soldo |
| Date: | August 1998 |
| Date Deposited: | 06 Mar 2012 17:51 |
| Last Modified: | 14 Feb 2017 20:24 |
| PMCID: | PMC109901 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/25191 |
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