The degradation by ribonuclease of substrates other than ribonucleic acid

McDonald, M.R., Kaufmann, B. P. (September 1954) The degradation by ribonuclease of substrates other than ribonucleic acid. J Histochem Cytochem, 2 (5). pp. 387-94. ISSN 0022-1554 (Print)0022-1554 (Linking)

URL: https://www.ncbi.nlm.nih.gov/pubmed/13192328
DOI: 10.1177/2.5.387

Abstract

These experiments support the premise which is the basis for cytochemical procedures that employ ribonuclease for the identification of ribonucleic acid, namely, that the substrate specifically degraded by ribonuclease is ribonucleic acid. The reduction in Feulgen stainability of chromatin effected by ribonuclease has been shown to be due to an intracellular deoxyribonuclease, which hydrolyzes intracellular deoxyribonucleic acid only after ribonucleic acid has been removed. The degradation of apurinic acid by ribonuclease can be duplicated by other proteins.

Item Type: Paper
Uncontrolled Keywords: *Dna *Rna *Ribonucleases *Nucleases
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > ribonuclease
CSHL Authors:
Communities: The Carnegie Institution Department of Genetics
Depositing User: Matt Covey
Date: September 1954
Date Deposited: 23 Jan 2018 15:14
Last Modified: 23 Jan 2018 15:14
Related URLs:
URI: http://repository.cshl.edu/id/eprint/35953

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