Patterned Photostimulation in the Brain

Anselmi, Francesca, Banerjee, Arkarup, Albeanu, Dinu F. (2015) Patterned Photostimulation in the Brain. In: New Techniques in Systems Neuroscience. Springer International Publishing, Cham, pp. 235-270. ISBN 978-3-319-12913-6

URL: https://link.springer.com/chapter/10.1007%2F978-3-...
DOI: 10.1007/978-3-319-12913-6_9

Abstract

Photostimulation has been instrumental in the past two decades for studying the structural synaptic plasticity and functional connectivity of neuronal circuits. With the advent of optogenetic strategies, this approach has been further expanded and used to identify the neuronal substrates of behavior via monitoring and modulating the activity of specific neuronal types in vivo. To date, however, photostimulation has been mainly implemented via full-field illumination and laser scanning protocols, which suffer from limited selectivity and stop short of generating asynchronous and spatially distributed neuronal firing patterns, characteristic for brain activity.

Item Type: Book Section
Subjects: organs, tissues, organelles, cell types and functions > organs types and functions > brain
Investigative techniques and equipment > optogenetics
CSHL Authors:
Communities: CSHL labs > Albeanu lab
Depositing User: Matt Covey
Date: 2015
Date Deposited: 29 Nov 2017 17:22
Last Modified: 29 Nov 2017 17:22
URI: http://repository.cshl.edu/id/eprint/35675

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