Architecting a distributed bioinformatics platform with iRODS and iPlant agave API

Wang, L., Van Buren, P., Ware, D. (2016) Architecting a distributed bioinformatics platform with iRODS and iPlant agave API. 2015 International Conference on Computational Science and Computational Intelligence (CSCI). pp. 420-423.

URL: http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arn...
DOI: 10.1109/CSCI.2015.121

Abstract

Over the past few years, cloud-based platforms have been proposed to address storage, management, and computation of large-scale data, especially in the field of genomics. However, for collaboration efforts involving multiple institutes, data transfer and management, interoperability and standardization among different platforms have imposed new challenges. This paper proposes a distributed bioinformatics platform that can leverage local clusters with remote computational clusters for genomic analysis using the unified bioinformatics workflow. The platform is built with a data server configured with iRODS, a computation cluster authenticated with iPlant Agave system, and web server to interact with the platform. A Genome-Wide Association Study workflow is integrated to validate the feasibility of the proposed approach. © 2015 IEEE.

Item Type: Paper
Uncontrolled Keywords: Agave API Big data Bioinformatics Cloud computing Data analysis Data storage IPlant
Subjects: bioinformatics
bioinformatics > computational biology
bioinformatics > genomics and proteomics > computers > computer hardware
bioinformatics > genomics and proteomics > computers > computer software
CSHL Authors:
Communities: CSHL labs > Ware lab
Depositing User: Matt Covey
Date Deposited: 09 May 2016 18:58
Last Modified: 09 May 2016 18:58
URI: http://repository.cshl.edu/id/eprint/32781

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving