Comment on "Widespread RNA and DNA sequence differences in the human transcriptome"

Lin, W., Piskol, R., Tan, M. H., Li, J. B. (March 2012) Comment on "Widespread RNA and DNA sequence differences in the human transcriptome". Science, 335 (6074). 1302; author reply 1302. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/22422964.1
DOI: 10.1126/science.1210624

Abstract

Li et al. (Research Articles, 1 July 2011, p. 53; published online 19 May 2011) reported widespread differences between the RNA and DNA sequences of the same human cells, including all 12 possible mismatch types. Before accepting such a fundamental claim, a deeper analysis of the sequencing data is required to discern true differences between RNA and DNA from potential artifacts.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics
organism description > animal > mammal > primates > hominids > human
organism description > animal > mammal
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > transcriptomes
CSHL Authors:
Communities: CSHL labs > Gingeras lab
Depositing User: Matt Covey
Date: 16 March 2012
Date Deposited: 30 Jan 2013 17:46
Last Modified: 30 Jan 2013 17:46
PMCID: NLM
Related URLs:
URI: http://repository.cshl.edu/id/eprint/26995

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