There is nothing 'incidental' about unrelated findings

Lyon, G. J. (2012) There is nothing 'incidental' about unrelated findings. Personalized Medicine, 9 (2). pp. 163-166. ISSN 17410541 (ISSN)

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URL: http://www.futuremedicine.com/doi/abs/10.2217/pme....
DOI: 10.2217/pme.11.98
Item Type: Paper
Additional Information: Cited By (since 1996): 1 Export Date: 22 October 2012 Source: Scopus Language of Original Document: English Correspondence Address: Lyon, G.J.; Institute for Genomic Medicine, Utah Foundation for Biomedical Research, Murray, UT, United States; email: LyonG1@email.chop.edu References: Rope, A.F., Wang, K., Evjenth, R., Using VAAST to identify an X linked disorder resulting in lethality in male infants due to N terminal acetyltransferase deficiency (2011) Am. J. Hum. Genet., 89 (1), pp. 28-43; Lyon, G.J., Personal account of the discovery of a new disease using next-generation sequencing interview by natalie Harrison (2011) Pharmacogenomics, 12 (11), pp. 1519-1523; Miki, Y., Swensen, J., Shattuck-Eidens, D., A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 (1994) Science, 266, pp. 66-71; Lyon, G.J., Jiang, T., Van Wijk, R., Exome sequencing and unrelated findings in the context of complex disease research: Ethical and clinical implications (2011) Discov. Med., 12, pp. 41-55; Greely, H.T., The uneasy ethical and legal underpinnings of large-scale genomic biobanks (2007) Annu. Rev. Genomics Hum. Genet., 8, pp. 343-364; Hayden, E.C., Secrets of the human genome disclosed: Meeting debates ethics of revealing genetic findings (2011) Nature, 478 (7367), p. 17; Biesecker, L.G., Exome sequencing makes medical genomics a reality (2010) Nat. Genet., 42, pp. 13-14; Chen, J.M., Ferec, C., Cooper, D.N., Revealing the human mutome (2010) Clin. Genet., 78, pp. 310-320; Kobelka, C.E., Exome sequencing: Expanding the genetic testing toolbox (2010) Clin. Genet., 78, pp. 132-134; Kuhlenbaumer, G., Hullmann, J., Appenzellerm, S., Novel genomic techniques open new avenues in the analysis of monogenic disorders (2011) Hum. Mutat., 32 (2), pp. 144-151; Vernooij, M.W., Ikram, M.A., Tanghe, H.L., Incidental findings on brain MRI in the general population (2007) N. Engl. J. Med., 357, pp. 1821-1828; Rodjan, F., De Graaf, P., Moll, A.C., Brain abnormalities on MR imaging in patients with retinoblastoma (2010) AJNR Am. J. Neuroradiol., 31, pp. 1385-1389; Orme, N.M., Fletcher, J.G., Siddiki, H.A., Incidental findings in imaging research: Evaluating incidence, benefit, and burden (2010) Arch. Intern. Med., 170, pp. 1525-1532; Bamshad, M.J., Ng, S.B., Bigham, A.W., Exome sequencing as a tool for mendelian disease gene discovery (2011) Nat. Rev. Genet., 12, pp. 745-755; Murphy, J., Scott, J., Kaufman, D., Geller, G., LeRoy, L., Hudson, K., Public expectations for return of results from large-cohort genetic research (2008) Am. J. Bioeth., 8, pp. 36-43; Haga, S.B., Tindall, G., O'Daniel, J.M., Public perspectives about pharmacogenetic testing and managing ancillary findings (2011) Genet. Test. Mol. Biomarkers, , 10.1089/gtmb.2011.0118 Epub ahead of print; O'Daniel, J., Haga, S.B., Public perspectives on returning genetics and genomics research results (2011) Public Health Genomics, 14, pp. 346-355; Tabor, H.K., Berkman, B.E., Hull, S.C., Bamshad, M.J., Genomics really gets personal: How exome and whole genome sequencing challenge the ethical framework of human genetics research (2011) Am. J. Med. Genet. A, 155 (12), pp. 2916-2924
Uncontrolled Keywords: ethics exome sequencing genetics incidental unrelated finding whole-genome sequencing data analysis gene sequence genomics human incidental finding medical information nomenclature priority journal review
Subjects: bioinformatics > genomics and proteomics
Communities: CSHL labs > Lyon lab
CSHL Authors: Lyon, Gholson
Depositing User: Matt Covey
Date Deposited: 10 Dec 2012 20:13
Last Modified: 10 Dec 2012 21:20
URI: http://repository.cshl.edu/id/eprint/26305

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