Zhao, Xi., Xuan, Z. Y., Zhang, M. Q. (February 2007) Boosting with stumps for predicting transcription start sites. Genome Biol, 8 (2). R17. ISSN 1465-6914 (Electronic)
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Abstract
Promoter prediction is a difficult but important problem in gene finding, and it is critical for elucidating the regulation of gene expression. We introduce a new promoter prediction program, CoreBoost, which applies a boosting technique with stumps to select important small-scale as well as large-scale features. CoreBoost improves greatly on locating transcription start sites. We also demonstrate that by further utilizing some tissue-specific information, better accuracy can be achieved.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Algorithms Computational Biology/ methods Databases, Genetic Genomics/ methods Promoter Regions (Genetics)/genetics Software Transcription Initiation Site RNA-POLYMERASE-II GENOME-WIDE ANALYSIS CORE PROMOTER DNA SEQUENCES ELEMENTS IDENTIFICATION RECOGNITION DATABASE VIEW |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription bioinformatics > genomics and proteomics > databases bioinformatics > genomics and proteomics > annotation > gene expression profiling annotation bioinformatics > quantitative biology bioinformatics > genomics and proteomics > annotation > sequence annotation bioinformatics > genomics and proteomics > computers > computer software |
| CSHL Authors: | |
| Communities: | CSHL labs > Zhang lab |
| Depositing User: | CSHL Librarian |
| Date: | 2 February 2007 |
| Date Deposited: | 29 Aug 2011 22:48 |
| Last Modified: | 11 Apr 2018 16:00 |
| PMCID: | PMC1852414 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/15299 |
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