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Number of items at this level: 107.

Paper

Delgado, Ana Paula, Nemajerova, Alice, Rao, Manisha, Li, Jinyu, Marchenko, Natalia, Preall, Jonathan, Moll, Ute, Egeblad, Mikala, Powers, Scott (2022) Single-cell genomic analysis of triple-negative breast cancer fibroblasts uncovers evolutionarily conserved features and potential therapeutic targets. bioRxiv. (Submitted)

Zhao, X., Powers, S. (August 2017) New Views into the Genetic Landscape of Metastatic Breast Cancer. Cancer Cell, 32 (2). pp. 131-133. ISSN 15356108

Chen, M., Nowak, D. G., Narula, N., Robinson, B., Watrud, K., Ambrico, A., Herzka, T. M., Zeeman, M. E., Minderer, M., Zheng, W., Ebbesen, S. H., Plafker, K. S., Stahlhut, C., Wang, V. M., Wills, L., Nasar, A., Castillo-Martin, M., Cordon-Cardo, C., Wilkinson, J. E., Powers, S., Sordella, R., Altorki, N. K., Mittal, V., Stiles, B. M., Plafker, S. M., Trotman, L. C. (March 2017) The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol, 216 (3). pp. 641-656. ISSN 0021-9525

Lee, H. J., Li, C. F., Ruan, D., Powers, S., Thompson, P. A., Frohman, M. A., Chan, C. H. (September 2016) The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation. Mol Cell, 63 (6). pp. 1021-33. ISSN 1097-2765

Scott, K. L., Powers, S. (August 2016) Functionally Assessing Candidate Drivers Advances Precision Cancer Medicine. Cancer Cell, 30 (2). pp. 187-189. ISSN 1535-6108

Gerhard, D. S., Clemons, P. A., Shamji, A. F., Hon, C., Wagner, B. K., Schreiber, S. L., Krasnitz, A., Sordella, R., Sander, C., Lowe, S. W., Powers, S., Smith, K., Aburi, M., Iavarone, A., Lasorella, A., Silva, J., Stockwell, B. R., Califano, A., Boehm, J. S., Vazquez, F., Weir, B. A., Hahn, W. C., Khuri, F. R., Moreno, C. S., Johns, M., Fu, H., Nikolova, O., Mendez, E., Gadi, V. K., Margolin, A. A., Grandori, C., Kemp, C. J., Warren, E. H., Riddell, S. R., McIntosh, M. W., Gevaert, O., Kuo, C. J., Ji, H. P., Dhruv, H., Finlay, D., Kiefer, J., Kim, S., Vuori, K., Berens, M. E., Hangauer, M., Boettcher, M., Weissman, J. S., Bivona, T. G., Bandyopadhyay, S., McManus, M. T., McCormick, F., Aksoy, O., Simonds, E. F., Zheng, T., Chen, J., An, Z., Balmain, A., Weiss, W. A., Chen, K., Liang, H., Scott, K. L., Mills, G. B., Posner, B. A., MacMillan, J., Minna, J., White, M., Roth, M. G., Jagu, S., Mazerik, J. (July 2016) Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Mol Cancer Res. ISSN 1557-3125 (Electronic)1541-7786 (Linking)

Li, J., Sordella, R., Powers, S. (June 2016) Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Sci Rep, 6. p. 27891. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Powers, S., Pollack, R. E. (April 2016) Inducing stable reversion to achieve cancer control. Nature Reviews Cancer, 16 (4). pp. 266-270. ISSN 1474-175X

Wang, X., Chen, M., Yu, X., Pornputtapong, N., Chen, H., Zhang, N., Powers, S., Krauthammer, M. (March 2016) Global copy number profiling of cancer genomes. Bioinformatics, 32 (6). pp. 926-928. ISSN 1367-4803

Wu, S., Powers, S., Zhu, W., Hannun, Y. A. (January 2016) Substantial contribution of extrinsic risk factors to cancer development. Nature, 529 (7584). pp. 43-7. ISSN 0028-0836

Bott, A. J., Peng, I. C., Fan, Y., Faubert, B., Zhao, L., Li, J., Neidler, S., Sun, Y., Jaber, N., Krokowski, D., Lu, W., Pan, J. A., Powers, S., Rabinowitz, J., Hatzoglou, M., Murphy, D. J., Jones, R., Wu, S., Girnun, G., Zong, W. X. (December 2015) Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metab, 22 (6). pp. 1068-77. ISSN 1550-4131

Montal, E. D., Dewi, R., Bhalla, K., Ou, L., Hwang, B. J., Ropell, A. E., Gordon, C., Liu, W. J., DeBerardinis, R. J., Sudderth, J., Twaddel, W., Boros, L. G., Shroyer, K. R., Duraisamy, S., Drapkin, R., Powers, R. S., Rohde, J. M., Boxer, M. B., Wong, K. K., Girnun, G. D. (November 2015) PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. Mol Cell, 60 (4). pp. 571-83. ISSN 1097-2765

Wang, X., Yu, X., Zhu, W., McCombie, W. R., Antoniou, E., Powers, R. S., Davidson, N. O., Li, E., Williams, J. (June 2015) A trimming-and-retrieving alignment scheme for reduced representation bisulfite sequencing. Bioinformatics, 31 (12). pp. 2040-2042. ISSN 1367-4803

Li, J., Chanrion, M., Sawey, E., Wang, T., Chow, E., Tward, A., Su, Y., Xue, W., Lucito, R., Zender, L., Lowe, S. W., Bishop, J. M., Powers, S. (March 2015) Reciprocal Interaction of Wnt and RXR-alpha Pathways in Hepatocyte Development and Hepatocellular Carcinoma. PLoS One, 10 (3). e0118480. ISSN 1932-6203

Powers, S. (March 2015) Cooperation between MYC and companion 8q genes in hepatocarcinogenesis. Hepatology, 61 (3). pp. 757-8. ISSN 0270-9139

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, T. W., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., Schirmacher, P., Zuber, J., Weiss, K. H., Powers, S., Malek, N.P., Eilers, M., Sipos, B., Lowe, S. W., Geffers, R., Laufer, S., Zender, L. (September 2014) In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer. Nature Medicine, 20 (10). pp. 1138-1146. ISSN 1078-8956

Catanzaro, J. M., Sheshadri, N., Pan, J. A., Sun, Y., Shi, C., Li, J., Powers, R. S., Crawford, H. C., Zong, W. X. (April 2014) Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nature Communications, 5. p. 3729. ISSN 20411723

Cleary, S. P., Jeck, W. R., Zhao, X. B., Chen, K., Selitsky, S. R., Savich, G. L., Tan, T. X., Wu, M. C., Getz, G., Lawrence, M. S., Parker, J. S., Li, J. Y., Powers, S., Kim, H., Fischer, S., Guindi, M., Ghanekar, A., Chiang, D. Y. (November 2013) Identification of Driver Genes in Hepatocellular Carcinoma by Exome Sequencing. Hepatology, 58 (5). pp. 1693-1702. ISSN 0270-9139

Revill, Kate, Wang, Tim, Lachenmayer, Anja, Kojima, Kensuke, Harrington, Andrew, Li, Jinyu, Hoshida, Yujin, Llovet, Josep M., Powers, R. Scott (September 2013) Genome-wide Methylation Analysis and Epigenetic Unmasking Identify Tumor Suppressor Genes in Hepatocellular Carcinoma. Gastroenterology, 145 (6). pp. 1424-1435. ISSN 0016-5085

Rajaram, M., Li, J., Egeblad, M., Powers, R. S. (September 2013) System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. PLoS Genetics, 9 (9). e1003789. ISSN 1553-7404 (Electronic)1553-7390 (Linking)

Rajaram, M., Zhang, J., Wang, T., Li, J., Kuscu, C., Qi, H., Kato, M., Grubor, V., Weil, R. J., Helland, A., Borrenson-Dale, A. L., Cho, K. R., Levine, D. A., Houghton, A. N., Wolchok, J. D., Myeroff, L., Markowitz, S. D., Lowe, S. W., Zhang, M., Krasnitz, A., Lucito, R., Mu, D., Powers, R. S. (June 2013) Two Distinct Categories of Focal Deletions in Cancer Genomes. PLoS ONE, 8 (6). e66264. ISSN 1932-6203 (Electronic)1932-6203 (Linking)

Cleary, S. P., Jeck, W. R., Zhao, X. B., Selitsky, S. R., Savich, G. L., Tan, T. X., Wu, M. C., Getz, G., Lawrence, M. S., Parker, J. S., Li, J. Y., Powers, S., Kim, H., Fischer, S. E., Guindi, M., Ghanekar, A., Chiang, D. Y. (April 2013) Identification of driver genes in hepatocellular carcinoma by exome sequencing. Cancer Research, 73 (8 (Sup). p. 4598. ISSN 0008-5472

Mo, Q., Wang, S., Seshan, V. E., Olshen, A. B., Schultz, N., Sander, C., Powers, R. S., Ladanyi, M., Shen, R. (March 2013) Pattern discovery and cancer gene identification in integrated cancer genomic data. Proceedings of the National Academy of Sciences of the United States of America, 110 (11). pp. 4245-4250. ISSN 00278424 (ISSN)

Eifert, C., Powers, R. S. (June 2012) From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets. Nat Rev Cancer, 12 (8). pp. 572-578. ISSN 1474-1768 (Electronic)1474-175X (Linking)

Cai, C. L., Rajaram, M., Zhou, X., Liu, Q., Marchica, J., Li, J. Y., Powers, R. S. (May 2012) Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B. Cell Cycle, 11 (9). pp. 1773-1781. ISSN 1538-4101

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, A. R., Simon, J., Zhang, J., Luo, W. J., Hicks, J., Zender, L., Wang, X. W., Powers, S., Wigler, M., Lowe, S. W. (May 2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8212-8217. ISSN 0027-8424

Mazurek, A., Luo, W., Krasnitz, A., Hicks, J., Powers, R. S., Stillman, B. (2012) DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. Cancer Discovery, 2 (9). pp. 812-825. ISSN 21598274 (ISSN)

Liu-Sullivan, N., Zhang, J., Bakleh, A., Marchica, J., Li, J., Siolas, D., Laquerre, S., Degenhardt, Y. Y., Wooster, R., Chang, K., Hannon, G. J., Powers, S. (December 2011) Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1). Oncotarget, 2 (12). pp. 1254-64. ISSN 1949-2553 (Electronic) 1949-2553 (Linking)

Storm, P., Aits, S., Puthia, M. K., Urbano, A., Northen, T., Powers, S., Bowen, B., Chao, Y., Reindl, W., Lee, D. Y., Sullivan, N. L., Zhang, J., Trulsson, M., Yang, H., Watson, J. D., Svanborg, C. (June 2011) Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Oncogene, 30 (48). pp. 4765-4779. ISSN 09509232 (ISSN)

Sawey, E. T., Chanrion, M., Cai, C., Wu, G., Zhang, J., Zender, L., Zhao, A., Busuttil, R. W., Yee, H., Stein, L. D., French, D. M., Finn, Richard S, Lowe, S. W., Powers, S. (March 2011) Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening. Cancer Cell, 19 (3). pp. 347-358. ISSN 1535-6108

Cabal, R., Khanin, R., Viali, A., Socci, N., Lucito, R., Olshen, A., Zhang, J., Gerald, W., Powers, S., Ladanyi, M. (February 2011) Testing and Validating High Throughput Genomic Analysis of FFPE Samples: Systematic Gene Expression Differences between Matched Frozen and FFPE Samples Due to Rapid mRNA Degradation Signals. Modern Pathology, 24. p. 1875. ISSN 0893-3952

Schreiber, S. L., Shamji, A. F., Clemons, P. A., Hon, C., Koehler, A. N., Munoz, B., Palmer, M., Stern, A. M., Wagner, B. K., Powers, S., Lowe, S. W., Guo, X., Krasnitz, A., Sawey, E. T., Sordella, R., Stein, L. D., Trotman, L. C., Califano, A., Dalla-Favera, R., Ferrando, A., Iavarone, A., Pasqualucci, L., Silva, J., Stockwell, B. R., Hahn, W. C., Chin, L., DePinho, R. A., Boehm, J. S., Gopal, S., Huang, A., Root, D. E., Weir, B. A., Gerhard, D. S., Zenklusen, J. C., Roth, M. G., White, M. A., Minna, J. D., MacMillan, J. B., Posner, B. A. (September 2010) Towards patient-based cancer therapeutics. Nature Biotechnology, 28 (9). pp. 904-906.

Trotman, L. C., Powers, S. (July 2010) New views into the prostate cancer genome. Cancer Cell, 18 (1). pp. 1-2. ISSN 1878-3686 (Electronic) 1535-6108 (Linking)

Degenhardt, Y., Greshock, J., Laquerre, S., Gilmartin, A. G., Jing, J., Richter, M., Zhang, X., Bleam, M., Halsey, W., Hughes, A., Moy, C., Liu-Sullivan, N., Powers, S., Bachman, K., Jackson, J., Weber, B., Wooster, R. (July 2010) Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability. Molecular Cancer Therapeutics, 9 (7). pp. 2079-2089. ISSN 1535-7163

Oliver, T. G., Mercer, K. L., Sayles, L. C., Burke, J. R., Mendus, D., Lovejoy, K. S., Cheng, M. H., Subramanian, A., Mu, D., Powers, S., Crowley, D., Bronson, R. T., Whittaker, C. A., Bhutkar, A., Lippard, S. J., Golub, T., Thomale, J., Jacks, T., Sweet-Cordero, E. A. (April 2010) Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes & Development, 24 (8). pp. 837-852. ISSN 0890-9369

Bric, A., Miething, C., Bialucha, C. U., Scuoppo, C., Zender, L., Krasnitz, A., Xuan, Z., Zuber, J., Wigler, M. H., Hicks, J. B., McCombie, W. R., Hemann, M. T., Hannon, G. J., Powers, S., Lowe, S. W. (October 2009) Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell, 16 (4). pp. 324-35. ISSN 1535-6108

Hsu, D. S., Acharya, C. R., Balakumaran, B. S., Riedel, R. F., Kim, M. K., Stevenson, M., Tuchman, S., Mukherjee, S., Barry, W., Dressman, H. K., Nevins, J. R., Powers, S., Mu, D., Potti, A. (March 2009) Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proc Natl Acad Sci U S A, 106 (13). pp. 5312-5317. ISSN 0027-8424 (Print)1091-6490 (Electronic)

Starr, T. K., Allaei, R., Silverstein, K. A. T., Staggs, R. A., Sarver, A. L., Bergemann, T. L., Gupta, M., O'Sullivan, M. G., Matise, I., Dupuy, A. J., Collier, L. S., Powers, S., Oberg, A. L., Asmann, Y. W., Thibodeau, S. N., Tessarollo, L., Copeland, N. G., Jenkins, N. A., Cormier, R. T., Largaespada, D. A. (March 2009) A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer. Science, 323 (5922). pp. 1747-1750. ISSN 0036-8075

Keng, V. W., Villanueva, A., Chiang, D. Y., Dupuy, A. J., Ryan, B. J., Matise, I., Silverstein, K. A. T., Sarver, A., Starr, T. K., Akagi, K., Tessarollo, L., Collier, L. S., Powers, S., Lowe, S. W., Jenkins, N. A., Copeland, N. G., Llovet, J. M., Largaespada, D. A. (March 2009) A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nature Biotechnology, 27 (3). pp. 264-274. ISSN 1087-0156

Silva, J. M., Ezhkova, E., Silva, J., Heart, S., Castillo, M., Campos, Y., Castro, V., Bonilla, F., Cordon-Cardo, C., Muthuswamy, S. K., Powers, S., Fuchs, E., Hannon, G. J. (2009) Cyfip1 Is a Putative Invasion Suppressor in Epithelial Cancers. Cell, 137 (6). pp. 1047-1061. ISSN 00928674 (ISSN)

Sangha, N., Wu, R., Kuick, R., Powers, S., Mu, D., Fiander, D., Yuen, K., Katabuchi, H., Tashiro, H., Fearon, E. R., Cho, K. R. (December 2008) Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations. Neoplasia, 10 (12). pp. 1362-72.

Zender, L., Xue, W., Zuber, J., Semighini, C. P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J. M., Schirmacher, P., McCombie, W. R., Wigler, M. H., Hicks, J. B., Hannon, G. J., Powers, S., Lowe, S. W. (November 2008) An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer. Cell, 135 (5). pp. 852-864. ISSN 0092-8674

Miao, J., Mu, D., Ergel, B., Singavarapu, R., Duan, Z., Powers, S., Oliva, E., Orsulic, S. (November 2008) Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model. Int J Cancer, 123 (9). pp. 2041-7.

Xue, W., Krasnitz, A., Lucito, R., Sordella, R., Van Aelst, L., Cordon-Cardo, C., Singer, S., Kuehnel, F., Wigler, M. H., Powers, S., Zender, L., Lowe, S. W. (June 2008) DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development, 22 (11). pp. 1439-44. ISSN 0890-9369

Sinclair, A. M., Rogers, N., Busse, L., Archibeque, I., Brown, W., Kassner, P. D., Watson, J. E. V., Arnold, G. E., Nguyen, K. C. Q., Powers, S., Elliott, S. (March 2008) Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells. British Journal of Cancer, 98 (6). pp. 1059-1067. ISSN 0007-0920

Degenhardt, Y. Y., Wooster, R., McCombie, R. W., Lucito, R., Powers, S. (February 2008) High-content analysis of cancer genome DNA alterations. Current Opinion in Genetics & Development, 18 (1). pp. 68-72.

Powers, S., Mu, D. (January 2008) Genetic similarities between organogenesis and tumorigenesis of the lung. Cell Cycle, 7 (2). 200 - 204 .

Kendall, J. T., Liu, Q. A., Bakleh, A., Krasnitz, A., Nguyen, K. C. Q., Lakshmi, B., Gerald, W., Powers, S., Mu, D. (October 2007) Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer. Proc Natl Acad Sci U S A, 104 (42). pp. 16663-16668. ISSN 0027-8424 (Print)

Pelham, R. J., Rodgers, L., Hall, I. M., Lucito, R., Nguyen, K. C. Q., Navin, N. E., Hicks, J. B., Mu, D., Powers, S., Wigler, M. H., Botstein, D. (December 2006) Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A, 103 (52). pp. 19848-19853. ISSN 0027-8424

Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M. H., Hannon, G. J., Mu, D., Lucito, R., Powers, S., Lowe, S. W. (June 2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell, 125 (7). pp. 1253-67. ISSN 0092-8674 (Print)

van der Horst, E. H., Degenhardt, Y. Y., Strelow, A., Slavin, A., Chinn, L., Orf, J., Rong, M., Li, S., See, L. H., Nguyen, K. Q., Hoey, T., Wesche, H., Powers, S. (November 2005) Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proceedings of the National Academy of Sciences of the United States of America, 102 (44). pp. 15901-6. ISSN 0027-8424

Zender, L., Spector, M. S., Xue, W., Flemming, P., Mu, D., Cordon-Cardo, C., Powers, S., Hannon, G. J., Lucito, R., Lowe, S. W. (October 2005) Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma. Hepatology, 42 (4). 244A-244A. ISSN 0270-9139

He, L., Thomson, J. M., Hemann, M. T., Hernando-Monge, E., Mu, D., Goodson, S., Powers, S., Cordon-Cardo, C., Lowe, S. W., Hannon, G. J., Hammond, S. M. (June 2005) A microRNA polycistron as a potential human oncogene. Nature, 435 (7043). pp. 828-33. ISSN 0028-0836

Zender, L., Xue, W., Cordon-Cardo, C., Hannon, G. J., Lucito, R., Powers, S., Flemming, P., Spector, M. S., Lowe, S. W. (2005) Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors. Cold Spring Harb Symp Quant Biol, 70 (1). pp. 251-261. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

Harrison, M., Li, J., Degenhardt, Y., Hoey, T., Powers, S. (August 2004) Wip1-deficient mice are resistant to common cancer genes. Trends in Molecular Medicine, 10 (8). pp. 359-361. ISSN 1471-4914

Lucito, R., Healy, J., Alexander, J., Reiner, A., Esposito, D., Chi, M. Y., Rodgers, L., Brady, A., Sebat, J., Troge, J. E., West, J. A., Rostan, S., Nguyen, K. C. Q., Powers, S., Ye, K. Q., Olshen, A., Venkatraman, E., Norton, L., Wigler, M. H. (October 2003) Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation. Genome Research, 13 (10). pp. 2291-2305. ISSN 1088-9051

Pei, L., Wiser, O., Slavin, A., Mu, D., Powers, S., Jan, L. Y., Hoey, T. (June 2003) Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proceedings of the National Academy of Sciences of the United States of America, 100 (13). pp. 7803-7. ISSN 0027-8424

Mu, D., Chen, L. Y., Zhang, X. P., See, L. H., Koch, C. M., Yen, C., Tong, J. J., Spiegel, L., Nguyen, K. C. Q., Servoss, A., Peng, Y., Pei, L., Marks, J. R., Lowe, S. W., Hoey, T., Jan, L. Y., McCombie, W. R., Wigler, M. H., Powers, S. (March 2003) Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell, 3 (3). pp. 297-302. ISSN 1535-6108

Pei, L., Peng, Y., Yang, Y., Ling, X. B., Van Eyndhoven, W. G., Nguyen, K. C., Rubin, M., Hoey, T., Powers, S., Li, J. (October 2002) PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Cancer Res, 62 (19). pp. 5420-4. ISSN 0008-5472 (Print)0008-5472

Li, J., Yang, Y., Peng, Y., Austin, R. J., van Eyndhoven, G., Nguyen, K. C. Q., Gabriele, T., McCurrach, M. E., Marks, J. R., Hoey, T., Lowe, S. W., Powers, S. (June 2002) Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nature Genetics, 31 (2). pp. 133-134. ISSN 1061-4036

Shields, J. M., Der, C. J., Powers, S. (2001) Identification of Ras-regulated genes by representational difference analysis. Methods in Enzymology, 332. pp. 221-32. ISSN 00766879 (ISSN)

Lucito, R., West, J., Reiner, A., Alexander, J., Esposito, D., Mishra, B., Powers, S., Norton, L., Wigler, M. H. (November 2000) Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations. Genome Research, 10 (11). pp. 1726-1736. ISSN 1088-9051

Bhattacharya, S., Chen, L., Broach, J. R., Powers, S. (March 1995) Ras membrane targeting is essential for glucose signaling but not for viability in yeast. Proceedings of the National Academy of Sciences of the United States of America, 92 (7). pp. 2984-8. ISSN 0027-8424

Jung, V., Chen, L., Hofmann, S. L., Wigler, M. H., Powers, S. (March 1995) Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins. Mol Cell Biol, 15 (3). pp. 1333-42. ISSN 0270-7306 (Print)

Chen, L., Powers, S. (1995) RAS in yeast: complementation assays for test of function. Methods in Enzymology, 255. pp. 465-8. ISSN 00766879 (ISSN)

Hart, M., Powers, S. (1995) Ras-Cdc25 and Rho-Dbl binding assays: complex formation in vitro. Methods in Enzymology, 255. pp. 129-35. ISSN 00766879 (ISSN)

Chen, L., Powers, S. (September 1994) A mutation in the effector region of Ras2 can be partially suppressed by alteration of a 'nonessential' region of Ras. Gene, 147 (1). pp. 107-10. ISSN 0378-1119 (Print)0378-1119

Chen, S. Y., Huff, S. Y., Lai, C. C., Der, C. J., Powers, S. (September 1994) Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor. Oncogene, 9 (9). pp. 2691-8. ISSN 0950-9232 (Print)0950-9232

Beranger, F., Cadwallader, K., Porfiri, E., Powers, S., Evans, T., de Gunzburg, J., Hancock, J. F. (May 1994) Determination of structural requirements for the interaction of Rab6 with RabGDI and Rab geranylgeranyltransferase. Journal of Biological Chemistry, 269 (18). pp. 13637-43. ISSN 0021-9258

Beranger, F., Paterson, H., Powers, S., de Gunzburg, J., Hancock, J. F. (January 1994) The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization. Mol Cell Biol, 14 (1). pp. 744-58. ISSN 0270-7306 (Print)0270-7306

Omer, C. A., Kral, A. M., Diehl, R. E., Prendergast, G. C., Powers, S., Allen, C. M., Gibbs, J. B., Kohl, N. E. (May 1993) Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases. Biochemistry, 32 (19). pp. 5167-76. ISSN 0006-2960 (Print)0006-2960

Lai, C. C., Boguski, M., Broek, D., Powers, S. (March 1993) Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol Cell Biol, 13 (3). pp. 1345-52. ISSN 0270-7306 (Print)0270-7306

Thorburn, A., Thorburn, J., Chen, S. Y., Powers, S., Shubeita, H. E., Feramisco, J. R., Chien, K. R. (January 1993) HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. Journal of Biological Chemistry, 268 (3). pp. 2244-9. ISSN 0021-9258

Powers, S. (August 1992) Genetic analysis of ras homologs in yeasts. Semin Cancer Biol, 3 (4). pp. 209-18. ISSN 1044-579X (Print)1044-579x

Boguski, M. S., Murray, A. W., Powers, S. (April 1992) Novel repetitive sequence motifs in the alpha and beta subunits of prenyl-protein transferases and homology of the alpha subunit to the MAD2 gene product of yeast. The New Biologist, 4 (4). pp. 408-11. ISSN 1043-4674 (Print)1043-4674

Ruggieri, R., Bender, A., Matsui, Y., Powers, S., Takai, Y., Pringle, J. R., Matsumoto, K. (February 1992) RSR1, a ras-like gene homologous to Krev-1 (smg21A/rap1A): role in the development of cell polarity and interactions with the Ras pathway in Saccharomyces cerevisiae. Molecular and Cellular Biology, 12 (2). pp. 758-66. ISSN 0270-7306

He, B., Chen, P., Chen, S. Y., Vancura, K. L., Michaelis, S., Powers, S. (December 1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proceedings of the National Academy of Sciences of the United States of America, 88 (24). pp. 11373-7. ISSN 0027-8424

Kohl, N. E., Diehl, R. E., Schaber, M. D., Rands, E., Soderman, D. D., He, B., Moores, S. L., Pompliano, D. L., Ferro-Novick, S., Powers, S. (October 1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. Journal of Biological Chemistry, 266 (28). pp. 18884-8. ISSN 0021-9258

Kim, J. H., Powers, S. (August 1991) Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function. Molecular and Cellular Biology, 11 (8). pp. 3894-904. ISSN 0270-7306

Powers, S., Gonzales, E., Christensen, T., Cubert, J., Broek, D. (June 1991) Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant. Cell, 65 (7). pp. 1225-31. ISSN 0092-8674 (Print)0092-8674

Powers, S. (April 1991) Protein prenylation: a modification that sticks. Current Biology, 1 (2). pp. 114-6. ISSN 0960-9822

Goodman, L. E., Judd, S. R., Farnsworth, C. C., Powers, S., Gelb, M. H., Glomset, J. A., Tamanoi, F. (December 1990) Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins. Proceedings of the National Academy of Sciences of the United States of America, 87 (24). pp. 9665-9. ISSN 0027-8424 (Print)0027-8424

Field, J., Vojtek, A., Ballester, R., Bolger, G., Colicelli, J., Ferguson, K., Gerst, J., Kataoka, T., Michaeli, T., Powers, S., Riggs, M., Rodgers, L., Wieland, I., Wheland, B., Wigler, M. H. (April 1990) Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein. Cell, 61 (2). pp. 319-327. ISSN 0092-8674

Powers, S., O'Neill, K., Wigler, M. H. (February 1989) Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae. Molecular & Cellular Biology, 9 (2). pp. 390-5. ISSN 0270-7306

Levin, L. R., Kuret, J., Johnson, K. E., Powers, S., Cameron, S., Michaeli, T., Wigler, M. H., Zoller, M. J. (April 1988) A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation. Science, 240 (4848). pp. 68-70.

Wigler, M. H., Field, J., Powers, S., Broek, D., Toda, T., Cameron, S., Nikawa, J., Michaeli, T., Colicelli, J., Ferguson, K. (1988) Studies of RAS function in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia on Quantitative Biology, 53 (2). pp. 649-55. ISSN 00917451 (ISSN)

Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S., Wigler, M. H. (March 1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell, 48 (5). pp. 789-800.

Michaelis, S., Anna, S. S., Powers, S., Wigler, M. H., Herskowitz, I. (1987) Yeast Mating Pheromone a-Factor and Its Relationship to Ras Proteins. Journal of Cellular Biochemistry. p. 261. ISSN 0730-2312

Powers, S., Michaelis, S., Broek, D., Ann-A, S. S., Field, J., Herskowitz, I., Wigler, M. H. (1986) RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor. Cell, 47 (3). pp. 413-422.

Birchmeier, C., Broek, D., Toda, T., Powers, S., Kataoka, T., Wigler, M. H. (1985) Conservation and divergence of RAS protein function during evolution. Cold Spring Harbor Symposia on Quantitative Biology, 50. pp. 721-725. ISSN 00917451 (ISSN)

Powers, S., Kataoka, T., Toda, T., Fasano, O., Wigler, M. H. (1985) Control of Yeast Adenyl-Cyclase by Ras Proteins. Federation Proceedings, 44 (3). R8-R8. ISSN 0014-9446

Kataoka, T., Powers, S., Cameron, S., Fasano, O., Goldfarb, M., Broach, J., Wigler, M. H. (1985) Functional homology of mammalian and yeast RAS genes. Cell, 40 (1). pp. 19-26.

Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K., Wigler, M. H. (1985) In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell, 40 (1). pp. 27-36.

Broach, J., Toda, T., Kataoka, T., Powers, S., Broek, D., Wigler, M. H. (1985) Ras Proteins Function Exclusively to Modulate Adenylate-Cyclase Activity in the Yeast Saccharomyces. DNA-a Journal of Molecular & Cellular Biology, 4 (1). p. 64. ISSN 0198-0238

Powers, S., Fisher, P. B., Pollack, R. (August 1984) Analysis of the reduced growth factor dependency of simian virus 40-transformed 3T3 cells. Molecular and Cellular Biology, 4 (8). pp. 1572-6. ISSN 0270-7306

Kataoka, T., Powers, S., McGill, C., Fasano, O., Strathern, J., Broach, J., Wigler, M. H. (June 1984) Genetic analysis of yeast RAS1 and RAS2 genes. Cell, 37 (2). pp. 437-445. ISSN 0092-8674

Murphy, R. F., Powers, S., Cantor, C. R. (May 1984) Endosome pH measured in single cells by dual fluorescence flow cytometry: rapid acidification of insulin to pH 6. Journal of Cell Biology, 98 (5). pp. 1757-62. ISSN 0021-9525

Murphy, R. F., Powers, S., Cantor, C. R., Pollack, R. (May 1984) Reduced insulin endocytosis in serum-transformed fibroblasts demonstrated by flow cytometry. Cytometry, 5 (3). pp. 275-80. ISSN 0196-4763 (Print)0196-4763

Powers, S., Kataoka, T., Fasano, O., Goldfarb, M., Strathern, J., Broach, J., Wigler, M. H. (March 1984) Genes in Saccharomyces cerevisiae encoding proteins with domains homologous to the mammalian ras proteins. Cell, 36 (3). pp. 607-612.

Murphy, R. F., Powers, S., Verderame, M., Cantor, C. R., Pollack, R. (May 1982) Flow cytofluorometric analysis of insulin binding and internalization by Swiss 3T3 cells. Cytometry, 2 (6). pp. 402-6. ISSN 0196-4763 (Print)0196-4763

Book Section

Powers, S. (1995) Cdc25p, Ira1p, and Ira2p. In: Guidebook to the small GTPases. Oxford University Press. ISBN 9780198599449

Powers, S., Michaelis, S. (1988) Biogenesis of yeast mating pheromone a-factor and Ras proteins. In: Molecular biology of intracellular protein sorting and organelle assembly: proceedings of a DuPont-UCLA symposium held in Taos, New Mexico, January 30-February 5, 1987. Liss. ISBN 9780845126752

Toda, T., Broek, D., Field, J., Michaeli, T., Cameron, S., Nikawa, J., Sass, P., Birchmeier, C., Powers, S., Wigler, M. H. (1987) Exploring the function of RAS oncogenes by studying the yeast Saccharomyces cerevisiae. In: Oncogenes and cancer : proceedings of the 17th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1986. Princess Takamatsu Symposia , 17 . Japan Scientific Societies Press, Tokyo, pp. 253-260. ISBN 4762205176

Wigler, M. H., Powers, S., Kataoka, T., Toda, T., Fasano, O., Matsumoto, K., Uno, I., Ishikawa, T., Broach, J. (1985) Function of Yeast Ras Genes. In: Genetics, cell differentiation, and cancer. Bristol-Myers cancer symposia, 7 (ED.). Academic Press, Orlando, pp. 153-164.

Wigler, M. H., Fasano, O., Taparowsky, E., Powers, S., Kataoka, T., Birnbaum, D., Shimizu, K., Goldfarb, M. (1984) Structure and Activation of Ras Genes. In: Oncogenes and viral genes. Cancer cells, 2 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 419-424. ISBN 0879691697

Pollack, R., Chen, S. Y., Powers, S., Verderame, M. (1984) Transformation mechanisms at the cellular level. In: Advances in Viral Oncology. Raven Press, pp. 3-28. ISBN 9780890049778

Powers, S., Alcorta, D., Nicholson, N., Pollack, R. (1982) Effects of calcium and hormones on the cytoskeleton and cell proliferation. In: Cold Spring Harbor Conferences on Cell Proliferation: Growth of cells in hormonally defined media. Cold Spring Harbor Laboratory. ISBN 9780879691561

This list was generated on Tue Dec 10 18:43:40 2024 EST.