The value of surgery for retroperitoneal sarcoma

Gholami, Sepideh, Jacobs, Charlotte D, Kapp, Daniel S, Parast, Layla M, Norton, Jeffrey A (2009) The value of surgery for retroperitoneal sarcoma. Sarcoma, 2009. p. 605840. ISSN 1357-714X

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Abstract

Introduction. Retroperitoneal sarcomas are uncommon large malignant tumors. Methods. Forty-one consecutive patients with localized retroperitoneal sarcoma were retrospectively studied. Results. Median age was 58 years (range 20-91 years). Median tumor size was 17.5 cm (range 4-41 cm). Only 2 tumors were <5 cm. Most were liposarcoma (44%) and high-grade (59%). 59% were stage 3 and the rest was stage 1. Median followup was 10 months (range 1-106 months). Thirty-eight patients had an initial complete resection; 15 (37%) developed recurrent sarcoma and 12 (80%) had a second complete resection. Patients with an initial complete resection had a 5-year survival of 46%. For all patients, tumor grade affected overall survival (P = .006). Complete surgical resection improved overall survival for high-grade tumors (P = .03). Conclusions. Tumor grade/stage and complete surgical resection for high-grade tumors are important prognostic variables. Radiation therapy or chemotherapy had no significant impact on overall or recurrence-free survival. Complete surgical resection is the treatment of choice for patients with initial and locally recurrent retroperitoneal sarcoma.

Item Type:	Paper
Subjects:	diseases & disorders > cancer diseases & disorders > cancer > cancer types > sarcoma
CSHL Authors:	Gholami, Sepideh
Communities:	CSHL labs > Gholami Lab
SWORD Depositor:	CSHL Elements
Depositing User:	CSHL Elements
Date:	2009
Date Deposited:	05 Oct 2023 20:20
Last Modified:	05 Oct 2023 20:20
PMCID:	PMC2760213
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/41163

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