Seasonal Variation in Stress Responses

Borniger, J. C., Cisse, Y. M., Nelson, R. J., Martin, L.B. (2017) Seasonal Variation in Stress Responses. In: Stress: Neuroendocrinology and Neurobiology. Chapter 41, 2 . Academic Press, pp. 411-419. ISBN 978-0-12-802175-0

DOI: 10.1016/B978-0-12-802175-0.00041-3


Winter is energetically demanding; thermogenic requirements are high and resources are scarce. This prolonged imbalance in energy intake and expenditure causes a stress response and glucocorticoid release. A chronic stress response typically results in pathology, but anticipation of seasonal stressors allows for the reorganization of endocrine, metabolic, immune, and neural processes to reduce energetic requirements. These trade-offs are mediated by differential investment in immune function and reproduction during times of low (fall and winter) and high (spring and summer) energy availability, respectively. Many nontropical animals monitor day length (i.e., photoperiod), in order to coordinate these seasonal adaptations. Much of the photoperiodic signal is transduced by pineal melatonin, as it is secreted inversely proportional to the absolute day length. This chapter will discuss seasonal changes in glucocorticoid release, binding globulin capacity, and receptor expression and their ultimate contributions to differential stress responses.

Item Type: Book Section
Subjects: organs, tissues, organelles, cell types and functions > tissues types and functions > biological clock
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > glucocorticoid receptor
diseases & disorders > physiological stress
CSHL Authors:
Communities: CSHL labs > Borniger lab
Depositing User: Adrian Gomez
Date: 2017
Date Deposited: 30 Jan 2020 20:54
Last Modified: 30 Jan 2020 20:54
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