TRPC Channels in Health and Disease

Tai, Y., Yang, S., Liu, Y., Shao, W. (May 2017) TRPC Channels in Health and Disease. Adv Exp Med Biol, 976. pp. 35-45. ISSN 0065-2598 (Print)0065-2598

DOI: 10.1007/978-94-024-1088-4_4


This chapter offers a brief introduction of the functions of TRPC channels in non-neuronal systems. We focus on three major organs of which the research on TRPC channels have been most focused on: kidney, heart, and lung. The chapter highlights on cellular functions and signaling pathways mediated by TRPC channels. It also summarizes several inherited diseases in humans that are related to or caused by TRPC channel mutations and malfunction. A better understanding of TRPC channels functions and the importance of TRPC channels in health and disease should lead to new insights and discovery of new therapeutic approaches for intractable disease.

Item Type: Paper
Uncontrolled Keywords: Cardiovascular Kidney Lung TRPCs
Subjects: diseases & disorders
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > ion channel
CSHL Authors:
Communities: CSHL labs > Van Aelst lab
Depositing User: Matt Covey
Date: May 2017
Date Deposited: 19 May 2017 20:15
Last Modified: 19 May 2017 20:15
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