A fractionating column for the analysis of nucleic acids

Mandell, Joseph D., Hershey, Alfred Day (1960) A fractionating column for the analysis of nucleic acids. Analytical Biochemistry, 1 (1). pp. 66-77.

URL: https://www.ncbi.nlm.nih.gov/pubmed/14420563
DOI: 10.1016/0003-2697(60)90020-8


A readily prepared fractionating column is described that separates several ribonucleic and deoxyribonucleic acids from each other, including the closely similar nucleic acids of T2 and T4 bacteriophages. The column also distinguishes DNA that has been denatured by heat and DNA that has been broken by hydrodynamic shear from the starting material. Some notes are recorded also concerning the preparation of nucleic acids from bacteria and phage by the phenol method.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
Investigative techniques and equipment
CSHL Authors:
Communities: The Carnegie Institution Department of Genetics
Depositing User: Matt Covey
Date: 1960
Date Deposited: 19 Apr 2017 19:32
Last Modified: 19 Apr 2017 19:32
Related URLs:
URI: https://repository.cshl.edu/id/eprint/34506

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