Fission yeast gene structure and recognition

Zhang, M. Q., Marr, T. G. (May 1994) Fission yeast gene structure and recognition. Nucleic Acids Res, 22 (9). pp. 1750-9. ISSN 0305-1048 (Print)

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DOI: 10.1093/nar/22.9.1750


A database of 210 Schizosaccharomyces pombe DNA sequences (524,794 bp) was extracted from GenBank (release number 81.0) and examined by a number of methods in order to characterize statistical features of these sequences that might serve as signals or constraints for messenger RNA splicing. The statistical information compiled includes splicing signal (donor, acceptor and branch site) profiles, translational initiation start profile, exon/intron length distributions, ORF distribution, CDS size distribution, codon usage table, and 6-tuple distribution. The information content of the various signals are also presented. A rule-based interactive computer program for finding introns called INTRON.PLOT has been developed and was used to successfully analyze 7 newly sequenced genes.

Item Type: Paper
Uncontrolled Keywords: Base Sequence Codon DNA, Fungal Exons Genes, Fungal Information Systems Introns Molecular Sequence Data Open Reading Frames Protein Biosynthesis RNA Splicing RNA, Fungal Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Schizosaccharomyces/ genetics
Subjects: bioinformatics
bioinformatics > genomics and proteomics > databases
organism description > yeast
CSHL Authors:
Communities: CSHL labs > Zhang lab
Depositing User: Matt Covey
Date: 11 May 1994
Date Deposited: 01 May 2015 20:04
Last Modified: 08 Nov 2017 16:05
PMCID: PMC308059
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