A distributed system for two-dimensional gel analysis

Monardo, P. J., Boutell, T., Garrels, J. I., Latter, G. I. (April 1994) A distributed system for two-dimensional gel analysis. Comput Appl Biosci, 10 (2). pp. 137-43.

URL: http://www.ncbi.nlm.nih.gov/pubmed/8019861
DOI: 10.1093/bioinformatics/10.2.137


The Quest II system is a new two-dimensional (2D) gel analysis software system for the construction and analysis of 2D gel protein databases. A new architectural approach to 2D gel software systems has been utilized. This architecture is based on a tightly coupled client/server model. There are three layers to the system architecture: (i) a database layer consisting of three database servers, (ii) a compute layer consisting of three compute servers and (iii) an extensible user interface layer currently consisting of user interface tools for linearization and merging of scanned images, the segmentation and detection of protein spots on the images, matching, editing, and analysis of gels. The ability to store and retrieve the large volume of spot data inherent in 2D gel analysis while utilizing database technology is demonstrated.

Item Type: Paper
Uncontrolled Keywords: Algorithms *Electrophoresis, Gel, Two-Dimensional Image Processing, Computer-Assisted *Software User-Computer Interface
Subjects: bioinformatics > genomics and proteomics > computers
bioinformatics > genomics and proteomics
bioinformatics > genomics and proteomics > computers > computer hardware
bioinformatics > genomics and proteomics > computers > computer software
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: April 1994
Date Deposited: 03 Aug 2015 16:20
Last Modified: 03 Aug 2015 16:20
Related URLs:
URI: https://repository.cshl.edu/id/eprint/31439

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving